![ChemicalBook](https://m.chemicalbook.com/Scripts/New/img/logo.png)
![N-Метиланилин структурированное изображение](/CAS/GIF/100-61-8.gif)
N-Метиланилин
- английское имяN-Methylaniline
- CAS №100-61-8
- CBNumberCB2671945
- ФормулаC7H9N
- мольный вес107.15
- EINECS202-870-9
- номер MDLMFCD00008283
- файл Mol100-61-8.mol
Температура плавления | -57 °C (lit.) |
Температура кипения | 196 °C (lit.) |
плотность | 0.989 g/mL at 25 °C (lit.) |
давление пара | 0.5 hPa (20 °C) |
показатель преломления | n |
Fp | 174 °F |
температура хранения | Store below +30°C. |
растворимость | water: slightly soluble30g/L |
пка | 4.84(at 25℃) |
форма | Liquid |
цвет | Clear yellow to brown |
РН | 7.6 (1g/l, H2O, 20℃) |
Запах | Moderate aniline-type. |
Растворимость в воде | 30 g/L |
Чувствительный | Air Sensitive |
Мерк | 14,6019 |
БРН | 741982 |
констант закона Генри | (x 10-5 atm?m3/mol): 1.19 at 25 °C (approximate - calculated from water solubility and vapor pressure) |
Пределы воздействия | NIOSH REL: TWA 0.5 ppm (2 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 2 ppm (9 mg/m3); ACGIH TLV: TWA 0.5 ppm (adopted). |
Диэлектрическая постоянная | 6.0(22℃) |
Стабильность | Incompatible with strong oxidizing agents. Discolours upon exposure to air. |
ИнЧИКей | AFBPFSWMIHJQDM-UHFFFAOYSA-N |
LogP | 1.66 at 20℃ |
Справочник по базе данных CAS | 100-61-8(CAS DataBase Reference) |
Рейтинг продуктов питания EWG | 1 |
FDA UNII | TH45GK410O |
Справочник по химии NIST | Aniline, N-methyl-(100-61-8) |
Система регистрации веществ EPA | N-Methylaniline (100-61-8) |
Коды опасности | T,N | |||||||||
Заявления о рисках | 23/24/25-33-50/53 | |||||||||
Заявления о безопасности | 28-36/37-45-60-61-28A | |||||||||
РИДАДР | UN 2294 6.1/PG 3 | |||||||||
OEB | B | |||||||||
OEL | TWA: 0.5 ppm (2 mg/m3) [skin] | |||||||||
WGK Германия | 3 | |||||||||
RTECS | BY4550000 | |||||||||
F | 8 | |||||||||
Температура самовоспламенения | 500 °C | |||||||||
TSCA | Yes | |||||||||
Класс опасности | 6.1 | |||||||||
Группа упаковки | III | |||||||||
кода HS | 29214200 | |||||||||
Банк данных об опасных веществах | 100-61-8(Hazardous Substances Data) | |||||||||
Токсичность | LD in rabbits (g/kg): 0.28 orally; in rabbits, cats (mg/kg): 24, 24 i.v. (Treon) | |||||||||
ИДЛА | 100 ppm | |||||||||
NFPA 704: |
|
рисовальное письмо(GHS)
-
рисовальное письмо(GHS)
-
сигнальный язык
опасность
-
вредная бумага
H319:При попадании в глаза вызывает выраженное раздражение.
H301+H311+H331:Токсично при проглатывании, при контакте с кожей или при вдыхании.
H410:Чрезвычайно токсично для водных организмов с долгосрочными последствиями.
H373:Может поражать органы (Нервная система) в результате многократного или продолжительного воздействия при вдыхании.
-
оператор предупредительных мер
P273:Избегать попадания в окружающую среду.
P280:Использовать перчатки/ средства защиты глаз/ лица.
P301+P310:ПРИ ПРОГЛАТЫВАНИИ: Немедленно обратиться за медицинской помощью. Прополоскать рот.
P302+P352+P312:ПРИ ПОПАДАНИИ НА КОЖУ: Промыть большим количеством воды. Обратиться за медицинской помощью при плохом самочувствии.
P304+P340+P311:ПРИ ВДЫХАНИИ: Свежий воздух, покой. Обратиться за медицинской помощью.
P314:В случае плохого самочувствия обратиться к врачу.
N-Метиланилин химические свойства, назначение, производство
Химические свойства
N-Methylaniline is a yellow to light brown oily liquid with a weak, ammonia-like odor. soluble in ethanol, ether, chloroform, slightly soluble in water. Turns reddishbrown if left standing.Физические свойства
Colorless to yellow to pale brown liquid with a faint, ammonia-like odor. Odor threshold concentration is 1.7 ppm (quoted, Amoore and Hautala, 1983).Использование
N-Methylaniline is used as a solvent and in organic synthesis. It is used in the production of cationic brilliant red FG, cationic pink B, reactive yellow brown KGR, etc. in the dye industry. N-methylaniline is an intermediate in the synthesis of the insecticide buprofezin and the herbicide mefenacet.Использование
N-methylaniline was used as raw material, and metal-organic skeleton material CAU-10pydc was used as catalyst to catalyze the reaction of CO2 with n-methylaniline to produce N-methyl-N-phenylformamide in mild conditions and green solvent acetonitrile[1]. Poly (N-methylaniline) (PNMA) was prepared by the electrooxidation of N-methylaniline in acidic aqueous solution. PNMA prepared in acidic aqueous solution with different organic solvents and anions had different conductivity. Such as the experimental group added acetonitrile, N, N-dimethylformamide and dimethylsulfoxide, and the experimental group which adding dimethylsulfoxide had the strongest conductivity[2].References:
[1] Zhiqiang Wang, Chenghua Deng, Xiao Liu, Wenmin Wang, Highly efficient conversion of CO2 into N-formamides catalyzed by a noble-metal-free aluminum-based MOF under mild conditions, 2023, 52, 11163-11167.
[2] Jun YANO , Hiroko YOSHIKAWA , Tomomi MUKAI , Sumio YAMASAKI , Akira KITANI, Effect of Anions and Added Organic Solvents of Polymerizing Solutions on the Conductivity of Poly (N-methylaniline), 2006, 74, 42-48.
Подготовка
N-methylaniline was synthesized by the reaction of aniline with dimethyl sulfate. Dimethyl sulfate was added dropwise to the mixed solution of aniline and water below 10°C, stirred for 1 h, and then added dropwise with 30% sodium hydroxide solution. The upper layer is the organic phase, and the lower layer is extracted with benzene. After the benzene is recovered from the extract, the obtained oil Chemicalbook-like substance is combined with the organic phase to obtain a mixture of aniline, N-methylaniline and N,N-dimethylaniline. The mixture was treated with sulfuric acid, and the aniline formed sulfate crystals which were filtered off. N,N-dimethylaniline can be converted to N-methylaniline by the following reaction.Определение
ChEBI: N-methylaniline is a methylaniline that is aniline carrying a methyl substituent at the nitrogen atom. It is a phenylalkylamine, a secondary amine and a methylaniline. It derives from an aniline.Общее описание
Chemical oxidation of N-methylaniline with dichromate (oxidant) has been studied by Raman spectroscopy.Опасность
Toxic by ingestion, inhalation, and skin absorption. Methemoglobinemia and central nervous system impairment.Угроза здоровью
Recommended Personal Protective Equipment: Approved respirator; rubber gloves; splash proof goggles; Symptoms Following Exposure: Inhalation causes dizziness and headache. Ingestion causes bluish discoloration (cyanosis) of lips, ear lobes, and fingernail beds. Liquid irritates eyes. Absorption through skin produces same symptoms as for ingestion; General Treatment for Exposure: INHALATION: remove victim to fresh air and call a physician at once; administer oxygen until physician arrives. INGESTION: give large amount of water; get medical attention at once. EYES or SKIN: flush with plenty of water for at least 15 min.; if cyanosis is present, shower with soap and warm water, with special attention to scalp and finger nails; remove any contaminated clothing; Toxicity by Inhalation (Threshold Limit Value): Data not available; Short-Term Inhalation Limits: Data not available; Toxicity by Ingestion: Data not available; Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: Data not available; Liquid or Solid Irritant Characteristics: Data not available; Odor Threshold: Data not available.Химическая реактивность
Reactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastic; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.Профиль безопасности
Poison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.Возможный контакт
The material is used as an intermediate in organic synthesis, as a solvent and as an acid acceptorКанцерогенность
N-methyl aniline (1.95 g/kg of food) given together with sodium nitrite (1.0 g/l of drinking water) to Swiss mice resulted in a 17% incidence of lung adenomas and a 14% incidence of malignant lymphomas; there were no carcinogenic effects in animals treated with Nmethyl aniline alone, suggesting that in vivo nitrosation is necessary for forming carcinogenic nitrosamines.In bacterial mutagenicity assays N-methyl aniline was negative with or without metabolic activation.
Экологическая судьба
Soil. Reacts slowly with humic acids or humates forming quinoidal structures (Parris, 1980).Перевозки
UN2294 N-Methylaniline, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.Методы очистки
Dry it with KOH pellets and fractionally distil it under vacuum. Acetylate, and the acetyl derivative is recrystallised to constant melting point (m 101-102o), then hydrolysed with aqueous HCl and distilled from zinc dust under reduced pressure. [Hammond & Parks J Am Chem Soc 77 340 1955, Beilstein 12 IV 241.]Утилизация отходов
Controlled incineration whereby oxides of nitrogen are removed from the effluent gas by scrubber, catalytic or thermal device.N-Метиланилин запасные части и сырье
сырьё
1of2
запасной предмет
- ASTRAZON PINK FG
- 2-хлор-N-(2,6-диметилфенил)ацетамид
- Pigment Green 18
- 4-(TRIMETHYL-UREIDO)-BENZENESULFONYL CHLORIDE
- N- (2-гидроксиэтил) -N-метиланилин
- N-METHYL-N-PHENYLCARBAMOYL CHLORIDE
- РИБИТИЛ-3,4-КСИЛИДИН *
- Basic Blue 54
- REACTIVE BLUE 4
- Михлера кетон
- Бензотиазол
- 1H-ПИРРОЛО[2,3-B]ПИРИДИН, 2-МЕТИЛ-
- ристалл Фиолетовый
- Метил Оранжевый
- Гексаметилдисилоксан
- Н-МЕТИЛ-Н-БЕНЗИЛАНИЛИН
- 4- (ДИМЕТИЛАМИНО) ФЕНИЛТИОЦИАНАТ
- Метиленовый голубой
- N-Chloromethyl-N-phenylaminoformyl chloride
- Buprofezin
1of8
N-Метиланилин поставщик
поставщик | телефон | страна | номенклатура продукции | благоприятные условия | |
---|---|---|---|---|---|
+86-13806087780 | China | 17367 | 58 | ||
+86-022-66880623 +8618622897568 |
China | 564 | 58 | ||
+86-592-6051114 +8618959220845 |
China | 6387 | 58 | ||
+undefined-86-25-86655873 | China | 114 | 58 | ||
+86-25-86736270 +86-15905172087 |
China | 103 | 58 | ||
+86-5925023701 +86-18900207489 |
China | 6044 | 58 | ||
+86-025-86618065 +86-13914714331 |
China | 73 | 58 | ||
025-52279164 | China | 79 | 58 | ||
+86 13288715578 +8613288715578 |
China | 12449 | 58 | ||
+86-13131129325 | China | 5867 | 58 |