Иприфлавон
- английское имяIpriflavone
- CAS №35212-22-7
- CBNumberCB0698496
- ФормулаC18H16O3
- мольный вес280.32
- EINECS609-092-2
- номер MDLMFCD00221719
- файл Mol35212-22-7.mol
химическое свойство
Температура плавления | 116-120 °C(lit.) |
Температура кипения | 363.04°C (rough estimate) |
плотность | 1.2170 (rough estimate) |
показатель преломления | 1.4700 (estimate) |
температура хранения | Sealed in dry,Room Temperature |
растворимость | DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM) DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM) DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM) Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM) |
форма | powder to crystal |
цвет | White to Almost white |
Мерк | 14,5074 |
InChI | InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3 |
ИнЧИКей | SFBODOKJTYAUCM-UHFFFAOYSA-N |
SMILES | C1OC2=CC(OC(C)C)=CC=C2C(=O)C=1C1=CC=CC=C1 |
LogP | 4.245 (est) |
Справочник по базе данных CAS | 35212-22-7(CAS DataBase Reference) |
Рейтинг продуктов питания EWG | 1 |
FDA UNII | 80BJ7WN25Z |
Код УВД | M05BX01 |
Коды опасности | Xi |
Заявления о рисках | 36/37/38 |
Заявления о безопасности | 24/25-36/37/39-27-26 |
WGK Германия | 2 |
RTECS | DJ3100500 |
кода HS | 29329990 |
рисовальное письмо(GHS)
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рисовальное письмо(GHS)
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сигнальный язык
предупреждение
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вредная бумага
H315:При попадании на кожу вызывает раздражение.
H319:При попадании в глаза вызывает выраженное раздражение.
H335:Может вызывать раздражение верхних дыхательных путей.
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оператор предупредительных мер
P261:Избегать вдыхания пыли/ дыма/ газа/ тумана/ паров/ аэрозолей.
P305+P351+P338:ПРИ ПОПАДАНИИ В ГЛАЗА: Осторожно промыть глаза водой в течение нескольких минут. Снять контактные линзы, если Вы ими пользуетесь и если это легко сделать. Продолжить промывание глаз.
Иприфлавон химические свойства, назначение, производство
Описание
Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It appears to be without significant side-effects.Химические свойства
white powderИспользование
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.Определение
ChEBI: Ipriflavone is a member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women. It has a role as a bone density conservation agent. It is a member of isoflavones and an aromatic ether.преимущество
Ipriflavone is used clinically to treat osteoporosis. Bodybuilders also use ipriflavone, but enough experimental data supports this purpose. It has been shown to have anti-inflammatory and antioxidant activity. It helps to reduce bone loss, increase bone density, and reduce the risk of developing osteoporosis. It has also been found to help reduce neuroinflammation . In addition, it has been found to help reduce the risk of certain types of cancer, improve cognitive function and reduce the risk of depression.Общее описание
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.Побочные эффекты
Ipriflavone should be taken under medical supervision only. It can produce side effects such as stomach pain, diarrhoea, dizziness, etc. It may have a sudden increase in the WBC count if administered for six months or more. When the treatment with Ipriflavone is on, it is suggested that the WBC count should be monitored.Иприфлавон запасные части и сырье
Иприфлавон поставщик
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