What is 2,2,6,6-Tetramethylpiperidine?
2,2,6,6-Tetramethylpiperidine, abbreviated TMP, HTMP, or TMPH, is an organic compound of the amine class. In appearance, it is a colorless liquid and has a "fishy", amine-like odor. This amine is used in chemistry as a hindered base (hindered amine). Although TMP finds limited use per se, its derivatives are a mainstay of hindered amine light stabilizers.
TMP is the starting material for an even stronger base lithium tetramethylpiperidide and the radical species TEMPO. Another non-nucleophilic base is N,N-diisopropylethylamine.
Preparation
Many routes for the synthesis of TMP have been reported. One method starts with a conjugate addition reaction of ammonia to phorone. The intermediate triacetone amine is then reduced in a Wolff-Kishner reaction.
Uses
2,2,6,6-Tetramethylpiperidine is used in the syntheses of HMP-Y1, Hibarimicinone and HMP-P1, tyrosine kinase inhibitors.
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Lastest Price from 2,2,6,6-Tetramethylpiperidine manufacturers
US $0.00/KG2024-06-16
- CAS:
- 768-66-1
- Min. Order:
- 25KG
- Purity:
- ≥99.0%
- Supply Ability:
- 5tons
US $10.00/Kg/Bag2022-06-02
- CAS:
- 768-66-1
- Min. Order:
- 1Kg/Bag
- Purity:
- 99%
- Supply Ability:
- 20 Tons