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Uses and Toxicity of 1-Methoxy-2-propanol

Nov 20，2024

1-Methoxy-2-propanol is a colorless liquid, it is used as an organic solvent with a wide variety of industrial and commercial uses.

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1-Methoxy-2-propanol Uses

1-Methoxy-2-propanol is mainly used as solvent, dispersant and diluent, as well as fuel antifreeze, extractant, etc. Used as solvent of nitrocellulose, compounding agent of brake oil and detergent, etc. Widely used in coatings and cleaners. It can be used as the active solvent of water-based coatings; Active solvent and coupling agent of solvent based printing ink; Solvent for ballpoint pens and pens; Coupling agents and solvents for household and industrial cleaners, derusting agents and hard surface cleaners; Solvents for agricultural pesticides; Mixed with propylene glycol n-butyl ether for glass cleaner formula.

1-Methoxy-2-propanol Toxicity

1-Methoxy-2-propanol is a mild toxicant. The toxicity is lower than that of the methyl, ethyl, and butyl ethers of ethylene glycol. The toxic symptoms from inhaling high concentrations are nausea, vomiting, and general anesthetic effects. In humans, toxic effects may be felt at exposure to a level of 3000–4000 ppm.The oral and dermal toxicities in test animals were low. The effects were mild depression of the central nervous system and a slight change in liver and kidney. The recovery was rapid. Irritant actions on the skin and eyes of rabbits were low LC50 value (rats): 7000 ppm /6 h, LD50 value (rats): 5660 mg/kg.

1-Methoxy-2-propanol Health hazard

Contact irritates skin, eyes and mucous membranes. Prolonged exposure to vapors may cause coughing, shortness of breath, dizziness and intoxication. Vapors heavier than air. Used as a solvent and as an antifreeze agent. The oral LD50 of rats was 6.6g/kg. The skin irritation is not obvious, but the toxic dose can be absorbed through the skin.

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