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网站主页 化工产品目录 生物化工 抑制剂 酪氨酸蛋白激酶/信号转导子和转录活化子抑制剂(JAK/STAT) JAK 抑制剂 (2E)-3-(6-溴-2-吡啶基)-2-氰基-N-[(1S)-1-苯基乙基]-2-丙烯酰胺 WP1066
  • WP1066

WP1066

2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylethyl]-, (2E)-
上海 更新日期:2019-11-14

上海化成医药化工有限公司

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联系人:Mr Shi
电话:021-13621923966拨打
手机:13621923966 拨打
邮箱:chem88@sohu.com

产品详情:

中文名称:
WP1066
英文名称:
2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylethyl]-, (2E)-
CAS号:
857064-38-1

Stat3 inhibitor III, WP1066 (WP10666) is a cell permeable AG 490 tyrphostin analog that effectively inhibits the STAT3 pathway. The inhibitor is a potent anti tumor agent as displayed in the growth inhibition of malignant glioma cell and acute myelogenous leukemia cells. Stat3 Inhibitor III, WP1066 has shown more potency as an antitumor agent than AG 490 when inhibiting malignant glioma growth in vitro. WP1066 also acts as an immune adjuvant by inducing proliferation of effector T cells and upregulating CD86 and CD80. In addition WP1066 has displayed inhibition of JAK-2 protein tyrosine kinase.

WP1066, sc-203282

公司简介

Shanghai H&C Chemical Co.,Ltd. is a innovative company engaged in organic intermediates, pharmaceutical ingredients, fine chemicals and custom synthesis. H&C have high experience from lab to semiwork and commercial production,and manufacturing team have high experience in cost saving, process improvement and quality control. H&C are high appraised by our customers for excellent quality and good price.

成立日期
注册资本
员工人数
年营业额
经营模式 工厂,定制,服务
主营行业 医药中间体,合成材料中间体,原料药,有机合成药,液晶中间体

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