Bafilomycin A1

B-1080 Bafilomycin A1, >98%
M.W. 622.83
C35H58O9
[88899-55-2]
Storage:  Store at or below -20 ºC.  Solubility:  Soluble in DMSO at 200 mg/mL; may react with methanol or ethanol, so these solvents are not recommended for stock solutions; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.  Appearance:  Clear film.  Disposal:  A
Specific, potent inhibitor of vacuolar ATPases.  Bowman, E.J., et al.  "Bafilomycins: A class of inhibitors of membrane ATPase from microorganisms, animal cells, and plant cells."  Proc. Natl. Acad. Sci. USA 85:  7972-7976 (1988).
Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.