aladdin 阿拉丁 B101389 巴佛洛霉素A1 88899-55-2 ≥95.0 %

中文名：巴佛洛霉素A1

英文名：Bafilomycin A1

英文别名：bafilomycin A1|88899-55-2|CHEMBL290814|CHEBI:22689|MFCD06795130|(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-{(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethy

纯度：≥95.0 %

货号：B101389

包装：1mg、5mg

Cas号：88899-55-2

存储温度：-20°C储存,充氩

产品介绍：

Bafilomycin A1 is a potent and selective inhibitor of V-ATPase (vacuolar-type (v-type) H+ ATPase) and belongs to a class of membrane ATPase inhibitors. The compound can inhibit E1E2 ATPases from sarcoplasmic reticulum, Escherichia coli, and ox brain versus F1F0 ATPases found in bacteria and mitochondria. Some of the more bafilomycin A1 affected ATPases include Neurospora and plant vacuoles, as well as chromaffin granules. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Research shows that Bafilomycin A1 can inhibit macroautophagy and promote apoptosis in colon cancer cells.A macrolide antibiotic and potent and selective inhibitor of vacuolar-type (v-type) H+ ATPase

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