aladdin 阿拉丁 B170472 蟾毒灵 465-21-4 98% (HPLC)

中文名：Bufalin

英文名：Bufalin

纯度：Moligand™，10mM in DMSO

货号：B424094

Cas号：465-21-4

存储温度：-80℃储存

运输条件：特低温运输

产品介绍：

Bufalin is a C-24 steroid with an α-pyrone ring positioned at C-17. It is present in the venom glands and skin of toad, Venenum Bufonis.Bufalin is a cardiotonic steroid[5] and is digoxin-like component of Chan Su.
Bufalin has been used:
• to test its effect on invasion and activation of nuclear factor kappa- B (NF-κB) cells and tumor necrosis factor-α (TNF-α) stimulated rheumatoid arthritis fibroblast-like synoviocytes (RAFLSs)
• as a nuclear receptor coactivator 3 (NCOA3) inhibitor in chondrocytes
• to test its anti-metastasis effect in lung cancer cells (NCI-H460) resistant to gefitinib

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