aladdin 阿拉丁 B170472 蟾毒灵 465-21-4 98% (HPLC)

中文名：蟾毒灵

英文名：Bufalin

中文别名：3β,14-二羟基-5β|20 (22)-丁二烯醇内酯,5β|20 (22)-丁二烯醇内酯-3β,14-二醇

英文别名：bufalin|465-21-4|CHEBI:517248|3-beta,14-Dihydroxy-5-beta-bufa-20,22-dienolide|3,14-Dihydroxy-bufa-20,22-dienolide|U549S98QLW|5-((3S,5R,8R,9S,10S,13R,14S,17R)-3,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2H-pyran-2-one|3bet

纯度：98% (HPLC)

货号：B170472

包装：10mg、250mg、50mg

Cas号：465-21-4

存储温度：避光,-20°C储存

产品介绍：

Bufalin is a C-24 steroid with an α-pyrone ring positioned at C-17. It is present in the venom glands and skin of toad, Venenum Bufonis.Bufalin is a cardiotonic steroid[5] and is digoxin-like component of Chan Su.
Bufalin has been used:
• to test its effect on invasion and activation of nuclear factor kappa- B (NF-κB) cells and tumor necrosis factor-α (TNF-α) stimulated rheumatoid arthritis fibroblast-like synoviocytes (RAFLSs)
• as a nuclear receptor coactivator 3 (NCOA3) inhibitor in chondrocytes
• to test its anti-metastasis effect in lung cancer cells (NCI-H460) resistant to gefitinib

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