武汉佰乐博生物技术有限公司

一、中文名称：

Stable Receptor Related Protein (RAP) LRP1 Inhibitor，稳定受体相关蛋白（RAP） LRP1抑制剂

二、产品描述

稳定受体相关蛋白（RAP）是脂蛋白受体相关蛋白1（LRP1）的拮抗剂。在中风后通过静脉注射给予RAP，可显著促进运动功能的恢复，并减少血脑屏障（BBB）的渗漏。RAP在控制血友病患者的出血风险方面也可能具有治疗潜力。这种分子能够以高亲和力与LRP1结合，并且在体外和体内均能抑制LRP1的功能。这表明，新型的RAP可能是一种有用的工具，有助于理解脂蛋白代谢、细胞信号传导、血脑屏障完整性的调节，以及血液凝固和纤维蛋白溶解等过程。

三、产品详情

名称：Stable Receptor Related Protein (RAP) LRP1 Inhibitor，稳定受体相关蛋白（RAP） LRP1抑制剂

货号：YHD89802

种属：Homo sapiens (Human)

预测分子量：42.00 kDa

性质：Recombinant

内毒素水平：Please contact with the lab for this information.

纯度：>90% as determined by SDS-PAGE.

应用：Inhibitor

状态：Lyophilized

保存溶液：Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

重悬：Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

运输：In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

稳定性和存储：Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名：Stable Receptor Related Protein (RAP) LRP1 Inhibitor, RAP, LRP1 Inhibitor

• 参考文献：

Lactoferrin stimulates osteoblast differentiation through PKA and p38 pathways independent of lactoferrin's receptor LRP1. PMID: 24877241

Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1. PMID: 14597676

Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain. PMID: 26013822

Midkine and LDL-receptor-related protein 1 contribute to the anchorage-independent cell growth of cancer cells. PMID: 17971413

详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司

网址：https://www.biolabreagent.com/product/101/18353.html

武汉佰乐博生物技术有限公司作为法国Antibodysystem品牌亚洲区授权总代理。提供近3万种蛋白、抗体等核心生命科学试剂，旨在为生命科学科研工作者提供专业、全面、可靠的试剂产品。

试剂 | 耗材 | 定制 | 实验服务 | 供应链

免费热线：027-65279366 /18108604356