长沙上禾生物Staherb罗汉果甜甙 Fructus monordicae extract核心功效与药理作用中英文简介

公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证

☎：19573130018 杨经理（微信同号）

中文｜Core Efficacy & Pharmacological Actions (CN)

罗汉果甜甙是以 罗汉果甜甙 V（Mogroside V） 为首的葫芦烷型三萜皂苷混合物，兼具天然零卡高倍甜味剂与多靶点药理活性分子双重属性。

一、核心功效（传统 + 现代）

1. 清热润肺、镇咳祛痰：归肺、大肠经，缓解肺热咳嗽、咽喉肿痛、急慢性咽炎、上呼吸道感染及肠燥便秘。

2. 零卡代糖、辅助控糖：甜度约蔗糖 150–300 倍，不升血糖、不刺激胰岛素剧烈波动，适用于糖尿病、肥胖、生酮配方。

3. 抗氧化、抗衰老：清除 ROS / 羟自由基，提升 SOD、GSH-Px 活性，降低 MDA，减轻氧化应激与线粒体损伤。

4. 抗炎免疫调节：抑制 TLR4/MyD88-NF-κB 与 MAPK 磷酸化，下调 TNF-α、IL-6、IL-1β、iNOS、COX-2。

5. 调脂保肝：激活 AMPK，调节 SREBP-1、PPARα/CPT-1，改善脂代谢；减轻肝组织病理损伤与肝纤维化。

6. 神经保护（研究级）：PD 模型中保护多巴胺能神经元，抑制神经炎症，依赖 AMPK/AKT-Nrf2 通路。

二、主要药理机制

• 糖代谢：促胰岛 β 细胞胰岛素分泌、抑制肠 α-葡萄糖苷酶/麦芽糖酶、AMPK 活化增敏胰岛素。

• 氧化应激：上调 Nrf2 → HO-1 / NQO1 / SOD / GPx 抗氧化酶系。

• 炎症：阻断 NF-κB 核转位与 TLR4-MyD88 信号，降低炎性介质释放。

• 呼吸道：舒缓咽喉黏膜刺激，减少咳嗽频次与气管痉挛（传统“润肺止咳”的现代对应）。

注：上禾 Staherb 该品项为食品/保健食品原料级提取物，上述药理多来自体外与动物实验，人体临床证据仍在积累，不得宣称治疗疾病。

English｜Core Efficacy & Pharmacological Actions (EN)

Staherb Monk Fruit Extract (Fructus Momordicae Extract) is a cucurbitane-type triterpene glycoside complex dominated by Mogroside V, functioning both as a natural zero-calorie high-intensity sweetener and a multi-target bioactive phytochemical.

Key Benefits (Traditional + Modern)

1. Lung-moistening, antitussive & expectorant: Traditionally used for heat-cough, sore throat, pharyngitis, URI and intestinal dryness constipation.

2. Zero-calorie sweetening & glycemic support: 150–300× sucrose sweetness, non-glycemic, insulin-friendly; suited for diabetic, obese and keto formulations.

3. Antioxidant & anti-aging: Scavenges ROS / hydroxyl radicals; upregulates SOD and GSH-Px, lowers MDA, protects mitochondrial homeostasis.

4. Anti-inflammatory & immunomodulatory: Suppresses TLR4/MyD88-NF-κB and MAPK phosphorylation; downregulates TNF-α, IL-6, IL-1β, iNOS, COX-2.

5. Lipid-modulating & hepatoprotective: Activates AMPK; regulates SREBP-1, PPARα/CPT-1; attenuates hepatic steatosis, injury and fibrosis.

6. Neuroprotection (research stage): Dopaminergic protection in Parkinson models via AMPK/AKT-Nrf2 and anti-neuroinflammatory effects.

Principal Pharmacological Mechanisms

• Glucose metabolism: Stimulates pancreatic β-cell insulin secretion, inhibits intestinal α-glucosidase/maltase, sensitizes insulin via AMPK activation.

• Oxidative stress: Activates Nrf2 → HO-1 / NQO1 / SOD / GPx antioxidant cascade.

• Inflammation: Blocks NF-κB nuclear translocation and TLR4-MyD88 signaling, reducing pro-inflammatory mediator release.

• Respiratory soothing: Reduces cough frequency and tracheal spasm, aligns with traditional “moisten lung, relieve throat” use.

Note: Staherb grade is a food/nutraceutical-grade extract. Most pharmacological data are in vitro / animal-based; human clinical evidence is accumulating. Not intended to diagnose, treat or cure any disease.

公司官网 http://www.staherb.com/ 资质:HALAL, KOSHER等认证

☎：19573130018 杨经理（微信同号）