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ChemicalBook Product Catalog API Nervous system drugs Antipsychotics Ziprasidone hydrochloride monohydrate

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Ziprasidone hydrochloride monohydrate NEW

$50.00 10mg

$81.00 25mg

$114.00 50mg

Min. Order
Purity99.95%
Cas No138982-67-9
Supply Ability10g
Update time2025-05-14

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

3YR

United States

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Chemical Properties

Product Name	Ziprasidone hydrochloride monohydrate
CAS No	138982-67-9
EC-No
Min. Order
Purity	99.95%
Supply Ability	10g
Release date	2025/05/14

Product Introduction

Bioactivity

Name	Ziprasidone hydrochloride monohydrate
Description	Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
In vitro	Ziprasidone blocked wild-type hERG currents in a voltage- and concentration-dependent manner in stably transfected HEK-293 cells with an IC(50) of 120 nM.Ziprasidone exhibited minimal hERG Ziprasidone significantly increased the time constant of the slow response to hERG current deactivation (-50 mV). ziprasidone is a 5-HT(1A) receptor agonist, as well as a 5-HT(2A), 5-HT(2C) and 5-HT(1B/1D) receptor antagonist. Ziprasidone is similar to the antidepressant promethazine in inhibiting the neuronal uptake of 5-HT and norepinephrine.Ziprasidone exhibits high affinity for human 5-HT receptors and human dopamine D(2) receptors.
In vivo	Ziprasidone blocked wild-type hERG currents in a voltage- and concentration-dependent manner in stably transfected HEK-293 cells with an IC(50) of 120 nM.Ziprasidone exhibited minimal hERG Ziprasidone significantly increased the time constant of the slow response to hERG current deactivation (-50 mV). ziprasidone is a 5-HT(1A) receptor agonist, as well as a 5-HT(2A), 5-HT(2C) and 5-HT(1B/1D) receptor antagonist. Ziprasidone is similar to the antidepressant promethazine in inhibiting the neuronal uptake of 5-HT and norepinephrine.Ziprasidone exhibits high affinity for human 5-HT receptors and human dopamine D(2) receptors.
Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 4.52 mg/mL (9.68 mM), Sonication is recommended.
Keywords	α2A-adrenergic receptor \| α1A-adrenergic receptor \| Ziprasidone hydrochloride monohydrate \| Ziprasidone hydrochloride Monohydrate \| Ziprasidone Hydrochloride \| Ziprasidone hydrochloride \| Serotonin Receptor \| serotonin \| norepinephrine transporter (NET) \| Inhibitor \| inhibit \| HistamineReceptor \| Histamine Receptor \| HEK-293 \| H1 receptor \| DopamineReceptor \| Dopamine Receptor \| Dopamine \| D3 \| D2 \| D1 \| CP-88059 \| CP88059 \| CP 88059 hydrochloride \| antipsychotic agent \| AdrenergicReceptor \| Adrenergic Receptor \| 5-hydroxytryptamine Receptor \| 5HTReceptor \| 5-HT7 \| 5-HT6 \| 5-HT2C \| 5-HT2A \| 5-HT1D \| 5-HT1B \| 5-HT1A \| 5-HT transporter \| 5-HT Receptor \| 5HT Receptor
Inhibitors Related	Alverine citrate \| Meclizine dihydrochloride \| Dapoxetine hydrochloride \| Clozapine N-Oxide \| Lidocaine \| Famotidine \| Octopamine hydrochloride \| Sodium butanoate \| D-Menthol \| Oxolinic acid \| Alginic acid \| Trazodone hydrochloride
Related Compound Libraries	Failed Clinical Trials Compound Library \| Bioactive Compound Library \| Pain-Related Compound Library \| Membrane Protein-targeted Compound Library \| Anti-Cancer Clinical Compound Library \| Drug Repurposing Compound Library \| Inhibitor Library \| FDA-Approved Drug Library \| Immunology/Inflammation Compound Library \| Bioactive Compounds Library Max \| GPCR Compound Library \| Anti-Cancer Drug Library

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