Manufacturer Provide Veterinary Raw Materialsul CAS599-79-1 Sulfasalazine
Introduction
1.Product Name: Sulfasalazine
2.Other Name: salicylazosulfapyridine;SALAZOSULFAPYRIDINE;SULFASALAZINE
3..CAS NO:599-79-1
4.Purity: 99%min
5.Appearance:White Powder
6.Molecular formula: C18H14N4O5S
7.Molecular weight:398.39
8.Melting Point :260-265 °C (dec.)(lit.)
9.Boiling Point :689.3±65.0 °C
10.Density :1.3742 g/mL at 20 °C
11.Storage:Keep in dark place,Inert atmosphere,Room temperature
Sulfasalazine is an antiinflammatory agent that inhibits GSH-H-transferase. Sulfasalazine largely inhibits NF-κB activation and induces apoptosis in T-lymphocytes. The compound also engages neutrophil apoptosis that can be abrogated by Tyr-K inhibitors, PKA inhibitors, or antioxidants. Sulfasalazine is shown to inhibit basic fibroblast growth factor-induced endothelial cell chemotaxis. Sulfasalazine is an inhibitor of TNFα and an activator of PPARγ.
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