Phentolamine Mesilate | 🔥 Non-Selective α-Blocker | 💊 Rapid Vasodilator for Hypertension & Raynaud’s | ✅ USP/EP Grade
🌐 Product Overview
Phentolamine Mesilate is a non-selective α-adrenergic receptor antagonist that rapidly reverses vasoconstriction and lowers blood pressure13. It is clinically used to manage hypertensive crises and Raynaud’s syndrome by blocking α1/α2 receptors, improving blood flow and reducing ischemia14. With >99% HPLC-verified purity, it meets stringent pharmacopeial standards for therapeutic applications24.
⚡ Key Benefits
- ⏱️ Rapid Onset
: Achieves blood pressure reduction within
30 minutes of administration. - 🎯 Dual α1/α2 Blockade
: Ensures balanced vasodilation and reduced cardiac workload34.
- 🧪 High Purity
: HPLC >99% and GC-MS validated, minimizing impurities.
🏥 Applications
- Hypertensive Emergencies
: Controls acute blood pressure spikes13.
- Raynaud’s Disease
: Alleviates vasospasm-induced pain and ischemia12.
- Diagnostic Testing
: Identifies pheochromocytoma via catecholamine reversal15.
✅ Quality Certifications
📈 Market Trends
The global hypertension drug market is projected to grow at 5.8% CAGR (2025–2030)6, driven by rising cardiovascular disease prevalence (affecting 1.3 billion adults worldwide)5. Phentolamine remains a critical agent in emergency and niche vascular therapies16.
Keywords: Non-selective alpha blocker, vasodilator drug, hypertensive crisis treatment, Raynaud’s syndrome medication, USP-grade API
Citations: 12 | Updated: Feb 2025


