Metoclopramide HCl
⚙️ D2/5-HT3 Antagonist | 💊 Antiemetic for GERD & Gastroparesis | 🌟 >99% Purity
Overview
Metoclopramide HCl is a dual-action antagonist targeting dopamine D2 and serotonin 5-HT3 receptors, accelerating gastric motility and alleviating nausea/vomiting in GERD and gastroparesis12. With >99% purity, it meets pharmaceutical-grade standards for clinical use23.
Key Features
⚡ Rapid Relief
: Symptomatic improvement within 30–60 minutes.
- 🎯 Dual Mechanism
: Blocks both D2 (gastric motility) and 5-HT3 (antiemetic) pathways16.
- 🧪 High Compatibility
: Adaptable for oral tablets, IV injections, and IM formulations2.
Applications
- GERD
: Reduces acid reflux and esophageal damage16.
- Diabetic Gastroparesis
: Enhances delayed gastric emptying6.
- Chemotherapy Support
: FDA-approved for oncology-related nausea2.
Quality Assurance
Market Insight
Global GI drug demand grows at 6.2% CAGR (2025–2030)5, driven by rising GERD cases (~20% adults in developed regions)1. Metoclopramide remains a cost-effective frontline therapy25.
Keywords: D2 antagonist, 5-HT3 blocker, antiemetic drug, GERD treatment, high-purity API
Citations: 12 | Updated: Feb 2025
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