Antazoline Hydrochloride (CAS 2508-72-7)
✦ Product Overview
Antazoline Hydrochloride (C₁₇H₂₀ClN₃, MW: 301.81) is a first-generation antihistamine and anticholinergic agent, widely recognized for its dual action in treating allergic reactions and cardiac arrhythmias. As a white crystalline powder, it exhibits high solubility in ethanol and limited solubility in water or ether12. Primarily used in pharmaceuticals and research, it addresses conditions like allergic rhinitis, conjunctivitis, and ventricular arrhythmias15.
✦ Key Advantages
🔹 High Purity: ≥99% (HPLC-verified), ensuring pharmaceutical-grade quality14.
🔹 Thermal Stability: Melting point 238°C, suitable for long-term storage at 2–8°C24.
🔹 Multi-Functionality: Combines antihistamine, anticholinergic, and local anesthetic effects15.
🔹 Regulatory Compliance: Meets USP42 standards for global pharmaceutical applications23.
✦ Applications
Human Medicine: Management of allergic reactions, arrhythmias, and preoperative sedation.
Ophthalmic Solutions: Topical treatment for allergic conjunctivitis.
Research: Study of histamine receptor mechanisms and drug development.
✦ Quality Assurance
Tested via HPLC, FTIR, and mass spectrometry, with batch-specific Certificates of Analysis (COAs). Stability validated per ICH guidelines and solubility confirmed in ethanol (≥20 mg/mL)14.
✦ Market Insights
The global antihistamine market is projected to grow at 5.2% CAGR (2025–2030), driven by rising allergy prevalence and demand for multifunctional therapeutic agents6.
China
