Norethindrone (CAS 68-22-4)
✦ Product Overview
Norethindrone (C₂₀H₂₆O₂, MW: 298.42) is a synthetic progestin widely used in hormone therapy. It regulates progesterone activity to treat menstrual disorders, endometriosis, and abnormal uterine bleeding, and serves as a contraceptive component. Its applications extend to pharmaceutical research and veterinary medicine12.
✦ Key Advantages
🔹 High Purity: ≥99% (HPLC-verified), ensuring pharmaceutical-grade quality56.
🔹 Thermal Stability: Melting point 205–206°C, stable for 2 years at 2–8°C or ambient storage13.
🔹 Regulatory Compliance: Meets USP42 standards for global pharmaceutical use24.
✦ Applications
Human Medicine: Management of endometriosis, menstrual irregularities, and contraceptive formulations.
Research: Reference standard for drug development and hormone studies.
Veterinary Use: Reproductive health therapy in animals.
✦ Quality Assurance
Tested via HPLC, FTIR, and mass spectrometry, with batch-specific Certificates of Analysis (COAs). Stability validated per ICH guidelines and solubility confirmed in DMSO/chloroform (≥50 mg/mL)35.
✦ Market Insights
The global hormone therapy market is projected to grow at 4.8% CAGR (2025–2030), driven by rising demand for reproductive health solutions and precision medicine23.
China
