Manufacturer Provide Veterinary Medicine Raw Powder CAS 83905-01-5 Azithromycin Dihydrate
Introduction
Name: Azithromycin
C.A.S NO. : 83905-01-5
Assay (%)(HPLC, Basis on drying):99%
Molecular formula: C38H72N2O12
Molecular weight : 748.98
Characteristic: White crystalline powder
Melting point: 113-115°C
Solubility: Almost insoluble in water, soluble in anhydrous ethanol and dichloromethane.
Application :
1.Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear i nfections, strep throat, pneumonia, typhoid, and sinusitis;
2.It has been used primarily to prevent bacterial infections in infants and those with weaker immune system3.It is also effective against certain sexually transmitted infections, such as non- gonococcal urethritis, chlamydia, and cervicitis;
4.Azithromycin is used for acute pharyngitis, acute tonsillitis caused by Streptococcus pyogenes;
5.Azithromycin is used for acute throat and tonsillitis which are caused by streptococcus pyogenes, otitis;
6.Azithromycin can treatment of media sinusitis acute bronchitis skin soft tissue infection which are caused by sensitive bacteria;
7.Azithromycin is also used for pneumonia urethritis cervicitis and so on.
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | A White or almost white crystalline powder | Conforms |
Solubility | Practically insoluble in water,freely soluble in anhydrous ethanol and in methylene chloride | Conforms |
Identification | IR | Conforms |
| HPLC |
|
Crystallinity | Meet the requirements | Conforms |
PH | 9.0 ~ 11.0 | 9.9 |
Related substances | Desosaminylazithromycin ≤0.3% | DL |
N-demethylazithromycin ≤0.7% | 0.001 |
Any other single impurity ≤1.0% | Conforms |
Total impurities≤3.0 % | 0.015 |
Residual solvents | Acetone ≤0.5% | 0.003 |
Loss on drying | 4.0 % ~ 5.0% | 0.045 |
Residue on Ignition | ≤0.3% | 0.0004 |
Melting point | 50 °C ~ 60 °C | 50 °C ~ 60 °C |
Sulphate ash | ≤0.1% | 0.0005 |
Heavy metals | ≤ 25 ppm | NMT25 ppm |
Assay ( calculated on the anhydrous basis) | 945 ug ~ 103 ug of azithromycin per mg | 982 ug/ mg |