Factory Provide Top Quality CAS 117772-70-0 Azithromycin Dihydrate Powder
Introduction
Product Name : Azithromycin Dihydrate
Othe name :AZITHROMYCIN 2-HYDRATE
CAS No. 117772-70-0
Molecular Formula: C38H74N2O13
MW: 767.01
Assay: 99%
Appearance: White powder
Melting Point :126°C (lit.)
Boiling Point :717℃ (rough estimate)
Storage :Keep in a cool, dry, dark location
Azithromycin has relatively broad but shallow antibacterial activity. It inhibits some Gram-positive bacteria, some Gram-negative bacteria, and many atypical bacteria.
A strain of gonorrhea reported to be highly resistant to azithromycin was found in the population in 2015. Neisseria gonorrhoeae is normally susceptible to azithromycin, but the drug is not widely used as monotherapy due to a low barrier to resistance development.Extensive use of azithromycin has resulted in growing Streptococcus pneumoniae resistance.
| Items | Specifications | Results |
| Character | White or almost white crystalline powder;odorless | white crystelline powder, odorless |
| Melting point | 242~246°C | 243.4~244.3°C |
| Identification | 1) IR spectra is consistent with CRS | complies |
| 2) The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | complies |
| Appearance of solution | colorless and clear liquid | colorless and clear liquid |
| Related substances | individual impurity≤1.0% | 0.24% |
| Total impuirties ≤2.0% | 0.70% |
| Loss on ignition | ≤0.5% | 0.32% |
| Residue on ignition | ≤0.1% | 0.05% |
| Heavy metals | Not more than 10 parts per million | Less than 10 parts per million |
| Assay | Not less than 98.0% of C18H14F3N3O6S(On dried basis) | 99.40% |
| Conclusion: | Complies with Enterprise Standard |
Application
1.Azithromycin Dihydrate is used for acute pharyngitis, acute tonsillitis caused by Streptococcus pyogenes.
2.Azithromycin is used for acute throat and tonsillitis which are caused by streptococcus pyogenes, otitis.
3.Azithromycin can treatment of media sinusitis acute bronchitis skin soft tissue infection which are caused by sensitive bacteria.
4.Azithromycin is also used for pneumonia urethritis cervicitis and so on.
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