| Name | ATP disodium trihydrate |
| Description | ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammation, which provides energy for the body's metabolism and also acts as a coenzyme in cells. |
| In vitro | ATP disodium trihydrate (5 mM; 1 h) with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.[3]
ATP disodium trihydrate (2 mM; 0.5-24 h) induces BMDM to secrete IL-1β, KC and MIP-2 in a caspase-1 activation-dependent manner.[4]
ATP disodium trihydrate promotes neutrophil chemotaxis.[4] |
| In vivo | ATP disodium trihydrate (50 mg/kg; ip) protects mice against bacterial infection and induces the secretion of IL-1β, KC, and MIP-2, promoting neutrophil recruitment.[4] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 0.9 mg/mL (1.5 mM), Sonication and heating to 80℃ are recommended.
H2O : 225.0 mg/mL (371.8 mM), Sonication is recommended.
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| Keywords | EndogenousMetabolite | Endogenous Metabolite | ATP disodium Trihydrate | ATP | Adenosine-5'-triphosphate disodium Trihydrate | Adenosine-5'-triphosphate |
| Inhibitors Related | Sucrose | Cysteamine hydrochloride | D(+)-Raffinose pentahydrate | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Natural Product Library | Drug Repurposing Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
United States
