1.Physical property
Appearance properties Prism crystals are obtained from ethanol. Melting point 169-171℃, relative density 1.293(21/4℃). Soluble in ethanol, acetone and hot water, insoluble in water, insoluble in petroleum ether and benzene. No smell, bitter taste. The pH of saturated aqueous solution is 5.5-6.5.
Melting point 168-172 °C(lit.)
Melting point 168-172 °C(lit.)
Boiling point 273.17°C (rough estimate)
Density 1,293 g/cm3
Vapor pressure 0.008Pa at 25℃
Refractive index 1.5810 (rough estimate)
Flash point 11 °C
Storage conditions Inert atmosphere,Room Temperature
Solubility ethanol: soluble 0.5M, transparent, colorless
Acidity coefficient (pKa)9.86±0.13(Predicted)
Form crystal or crystalline powder
Color White
PH 5.5-6.5 (H2O, 20℃)(saturated solution)
The Odor was odorless
Acid-base indicator discoloration ph range 5.5-6.5 (H? O, 20 °C) (saturated solution)
explosive limit 15%(V)
Water solubility 14 g/L (20 ºC)
Merck14, 47
BRN2208089
BCS Class3,4
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N
LogP1.098 at 25 ° C
CAS DataBase 103-90-2(CAS DataBase Reference)
(IARC) Classification of Carcinogens 3 (Vol. 50, 73) 1999
NIST Chemical Information Acetaminophen(103-90-2)
2.Use
Use 1
Used as antipyretic, analgesic, antirheumatic drug
Use 2
The product is an antipyretic analgesic, international non-proprietary drug name Paracetamol. It is the most commonly used non-anti-inflammatory antipyretic analgesic drug, antipyretic effect is similar to aspirin, the analgesic effect is weak, no anti-inflammatory and anti-rheumatic effect, is the best variety of acetanilide drugs. It is especially suitable for patients who cannot use carboxylic acids. For cold, toothache and other diseases. Acetaminophen is also an organic synthetic intermediate, a stabilizer of hydrogen peroxide, and a photographic chemical.
Use 3
Organic synthetic intermediates, stabilizers of hydrogen peroxide, photographic chemicals, non-anti-inflammatory antipyretic analgesics.
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