Chemical properties: prismatic crystals are obtained from ethanol. Melting point 169-171℃, relative density 1.293(21/4℃). Soluble in ethanol, acetone and hot water, insoluble in water, insoluble in petroleum ether and benzene. No smell, bitter taste. The pH of saturated aqueous solution is 5.5-6.5.
Use: It is an antipyretic and analgesic drug. It is the most commonly used non-anti-inflammatory antipyretic analgesic drug, antipyretic effect is similar to aspirin, the analgesic effect is weak, no anti-inflammatory and anti-rheumatic effect, Chemicalbook is the best variety of acetanilide drugs. It is especially suitable for patients who cannot use carboxylic acids. For cold, toothache and other diseases. Acetaminophen is also an organic synthetic intermediate, a stabilizer of hydrogen peroxide, and a photographic chemical.
Production method: Obtained by acetylation of para-aminophenol. Method 1: Add p-aminophenol to dilute acetic acid, then add glacial acetic acid, temperature rise to 150℃ for 7h, add acetic anhydride, reaction for 2h, check the end point, after qualified, cool to below 25℃, filter, wash until no acetic acid taste, shake dry, coarse product. Method 2: Distillation of para-aminophenol, glacial acetic acid and mother acid containing more than 50% of acid, evaporation of dilute acid at a rate of one-tenth of the total amount of distilled acid per hour, when the internal temperature rises to more than 130℃, sampling to check the residual amount of para-aminophenol is less than 2.5%, adding dilute acid (content of more than 50%), cooling crystallization. Filter, wash with a small amount of dilute acid first, and then wash with a lot of water until the filtrate is nearly colorless, and obtain rough products. The yield of method 1 is 90%, and the yield of method 2 is 90-95%. Refining method: When the water is heated to near boiling, the crude product is put into it. Heat up until fully dissolved, add activated carbon soaked in water, adjust with dilute acetic acid to pH=4.2-4.6, and boil for 10min. Press and filter the filtrate with a small amount of sodium bisulfite. Cooling to below 20℃, crystallization. Filter, wash, and dry the finished product of paracetamol.
Other production methods include:
(1) reduction of p-nitrophenol with zinc in glacial acetic acid and acetylation to obtain p-acetaminophen;
(2) The hydrazone generated by p-hydroxyacetophenone is placed in sulfuric acid solution, sodium nitrite is added, and acetaminophen is translocated.
Our advantages:
1) Timely communication, reply within 12 hours.You can leave any messages on our whatsapp or send email to us.
2)Selecting raw materials strictly,our products are the highest purity.
3)Reasonable and competitive price.
4) Free sample for your evaluation.Customers only need to undertake the shipping fee for delivery the samples to your destionation.
5)OEM/ODM Available.Trial order is available for testing after samples.
6) Packaging can be customized according to each buyers' special request.
We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.
We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.
Company Introduction
hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!
After Sales Service
1) Best quality in your requirement
2)Competitive price in china market
3)Mature technical support
4)Professional logistic support
5 )Full experience of large numberscontainers loading in chinese sea port
6 )Fast shipment by reputed shipping line
7) Packing with pallet as buyer's special request
8) Best service after shipment.
9) Cargoes together with container after-sales service available
10) Full experience in export
11)Raw materials from chinese origin
FAQ
What is the way you ship?
Express: FedEx, UPS, EMS, DHL, USPS, TNT, DPD, Aramex etc
Our way of shipping the products is universal and secure.
The company name and other contents related to pharmacy are not written on the package slips.
The way of packing is regularly changed for a secure delivery.
The packages are small in order to avoid unwelcomed questions . If the order is big, then it will be divided into two or more packages
Can the packages be trackable?
YES, we provide tracking number and you can track on internet.
Where do you ship to?
Worldwide.
Do you offer domestic shipping/remail shipping?
Yes we can ship to USA/UK/Canada/Australia/Germany etc warehouse first then to you.
Do you ensure your packing , what about customs, what happens if the package is retained?
We concern a lot about our safety system, we pack the orders as secure as possible. If a package is seized at customs, reships of seized orders will be done provided you have a copy of the letter to show us. If you receive a seizure letter, please contact us immediately with a scanned copy of the seizure letter, and also a new address to have your order reshipped to.
Which payment options are available?
Bitcoin
Western Union
Bank wire
MoneyGram
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