Product Name: Goserelin
Synonyms: GOSERELIN ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-GONADOTROPIN-RELEASING HORMONE ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-LHRH ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING FACTOR ACETATE SALT;(D-SER(TBU)6,AZAGLY10)-LUTEINIZING HORMONE-RELEASING HORMONE ACETATE SALT;PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2 ACETATE SALT;Goserlin;Goserelin-d7
CAS: 65807-02-5
MF: C61H88N18O16
MW: 1329.46
EINECS:
Product Categories: Pepetides;peptides;hormones
Mol File: 65807-02-5.mol
Goserelin Structure
Goserelin Chemical Properties
density 1.50±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: 20 mg/mL, clear, colorless
form white powder
pka 9.82±0.15(Predicted)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
Hazardous Substances Data 65807-02-5(Hazardous Substances Data)
MSDS Information
Provider Language
SigmaAldrich English
Goserelin Usage And Synthesis
Description Goserelin is an analog of luteinizing hormone-releasing hormone (LHRH) useful in the treatment of malignancies responsive to hormonal manipulation. Administered parenterally in a biodegradable depot, goserelin is reportedly as effective as orchidectomy and oophorectomy in patients with advanced prostate carcinoma and pre-menopausal breast cancer.
Chemical Properties White or almost white powder.
Originator ICI (United Kingdom)
Uses Labeled Goserelin, intended for use as an internal standard for the quantification of Goserelin by GC- or LC-mass spectrometry.
Brand name Zoladex (Zeneca).
China
