Factory Supply Folinic Acid CAS 58-05-9
Details
| Product Name | Folinic acid |
| MF | C20H23N7O7 |
| EINECS | 200-361-6 |
| Related categories | Pharmaceutical intermediates; Pharmaceutical Raw Materials |
| Melting point | 245°C (rough estimate) |
| Boiling point | 573.92°C |
| Pka | 3.1, 4.8, 10.4(at 25ºC) |
Application of Folinic acid:
L-folinic acid, as an anti-tumor antidote and an auxiliary drug against megaloblastic anemia, has a dose of 1/2 of that of folinic acid, which can participate in the reaction using folate as the source of one carbon unit without being reduced by dihydrofolate reductase, and can pass through the cell membrane actively or passively. The basic effect of L-folinic acid is the same as folic acid, but its effect is better than folic acid. At the same time, L-folinic acid can stimulate the growth and maturation of leukocytes and improve megaloblastic anemia.
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