罗红霉素钙盐(链霉菌属载体)
罗红霉素钙盐(链霉菌属载体) 性质
| 熔点 | 205-206 C |
|---|---|
| 闪点 | 87 °C |
| 储存条件 | −20°C |
| 溶解度 | 溶于 DMSO (10mg/ml)。也溶于乙醇或甲醇 |
| 形态 | 白色至类白色固体 |
| 颜色 | 白色至类白色 |
| 生物来源 | Streptomyces conglobatus |
| 敏感性 | Light Sensitive |
| BRN | 1416163 |
| 稳定性 | 可在-20°C下的DMSO或乙醇溶液保存长达2个月。 |
| InChIKey | WKRWUYKLUMMAKG-WYGBAUISSA-L |
罗红霉素钙盐(链霉菌属载体) 用途与合成方法
Calcium ionophore
Ionomycin is a Calcium ionophore and an antibiotic produced by
Streptomyces conglobatus
.
Addition of 2 μM Ionomycin to LCLC 103H cells causes an instantaneous increase in intracellular Ca
2+
concentration from 50 to 180 nM. DNA and protein analysis in Ionomycin-treated cultures revealed DNA fragmentation and PARP cleavage to an 85-kDa fragment typical of caspase-mediated apoptosis. Necrosis could be detected in ~1-5% of the Ionomycin treated cells. Caspase activation in whole cells was followed by monitoring the increase in activity against Ac-DEVD-amc following Ionomycin treatment.
Ionomycin-mediated cleavage and exosome release. Following Ionomycin exposure, medium conditioned by SKOV3ip cells had increased amounts of exosomes containing the L1-32 cleavage fragment.
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 22 |
| 安全说明 | 36 |
| WGK Germany | 3 |
| RTECS号 | NO0650000 |
| 危险等级 | 3 |
| 海关编码 | 29419090 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 急性毒性 类别4 经口 |
罗红霉素钙盐(链霉菌属载体) 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025-12-22 | HY-13434A | 罗红霉素钙盐(链霉菌属载体) | 56092-82-1 | 1 mg | 2380 |
| 2025-12-22 | HY-13434A | 罗红霉素钙盐(链霉菌属载体) | 56092-82-1 | 5mg | 4760 |
