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1-Benzyl-4-hydroxypiperidine

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1-Benzyl-4-hydroxypiperidine Basic information
1-Benzyl-4-hydroxypiperidine Chemical Properties
  • Melting point:61-63 °C(lit.)
  • Boiling point:127-128 °C2 mm Hg(lit.)
  • Density 1.0096 (rough estimate)
  • refractive index 1.5212 (estimate)
  • Flash point:121-123°C/0.7mm
  • form Crystalline Powder
  • pka14.87±0.20(Predicted)
  • color White to yellow
  • Sensitive Hygroscopic
  • BRN 146118
  • CAS DataBase Reference4727-72-4(CAS DataBase Reference)
  • NIST Chemistry Reference4-Piperidinol, 1-(phenylmethyl)-(4727-72-4)
Safety Information
MSDS
1-Benzyl-4-hydroxypiperidine Usage And Synthesis
  • Chemical PropertiesWHITE TO YELLOWISH CRYSTALLINE POWDER
  • UsesA piperidine based pesticide
  • Uses1-Benzyl-4-hydroxypiperidine is the reactant for synthesis of: Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist1 Fatty acid amide hydrolase inhibitors PI3 kinase-alpha inhibitors Flavonoid derivatives used as dual binding acetylcholinesterase inhibitors Urotensin-II receptor antagonists Rho kinase inhibitors.
  • Synthesis Reference(s)Journal of the American Chemical Society, 108, p. 3512, 1986 DOI: 10.1021/ja00272a059
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