Di-chlorobis[(1,2,3-)-1-phenyl-2-propenyl]dipalladium(II)

Di-chlorobis[(1,2,3-)-1-phenyl-2-propenyl]dipalladium(ii) is an important organic regant for the use of transition-metal-mediated organic syntheses. It can be used as a catalyst for the ammonia cross-coupling reactions to synthesize arylamines and conversion of aryl triflates to fluorides.

1. Precursor for the preparation of a palladium catalyst used in the carbonylative arylation of ketones, yielding vinylbenzoate compounds.
2. Precursor for the preparation of a palladium catalyst used in the Buchwald-Hartwig amination of (hetero)aryl chlorides.
3. Precursor for the preparation of a palladium catalyst used in the arylative dearomatization of phenols.
4. Versatile palladium precursor for the preparation of palladium catalysts used in the cross-coupling of aryl chlorides and amines , conversion of aryl triflates to aryl fluorides , and the α-arylation of aldehydes .

• Ammonia cross-coupling reactions to synthesize arylamines.
• Conversion of aryl triflates to fluorides.

A) In a double-necked flask equipped with magnetic stirring, 250 mL of distilled water was added and passed under argon gas for 30 min;

B) Continuing to keep under the flow of passed argon gas, PdCl2 (10 mmol,1.77 g,1 equiv) and KCl (20 mmol,1.42 g,2equiv) were added sequentially, and then the mouth of the flask was sealed with a rubber stopper, and the flask The mixture was stirred for 1 hour;

C) excess cinnamyl chloride (Ph-allyl)Cl (30mmol,4.58g,3equiv) was injected into the reaction flask through the rubber stopper, and the obtained system continued to react for 18 hours;

D) the reaction mixture was extracted with chloroform for 3 times, the organic phases were combined, dried with anhydrous MgSO4 and filtered, The solvent was removed under reduced pressure to obtain palladium chloride (-cinnamyl) dimer.