1,2-Distearoyl-sn-glycero-3-phosphoethanolamine is used in the generation of micelles and liposomes.
ChEBI: (R)-1,2-distearoylphosphatidylethanolamine is an optically active form of 1,2-distearoylphosphatidylethanolamine having (R)-configuration. It has a role as a mouse metabolite. It is an enantiomer of a (S)-1,2-distearoylphosphatidylethanolamine. It is a tautomer of a (R)-1,2-distearoylphosphatidylethanolamine zwitterion.
Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in biological membranes. Phosphatidylethanolamine is found in nervous tissue.
Phosphatidylethanolamine forms pure lipid structures. It modulates membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays an important role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.
The R-form is recrystallised from CHCl3/MeOH, and the ±-form is recrystallised from EtOH. [Bevan & Malkin J Chem Soc 2667 1951, Baer Can J Biochem Physiol 81 1758 1959, Beilstein 4 IV 1420.]
