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Cyclic AMP

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Cyclic AMP Basic information
Cyclic AMP Chemical Properties
  • Melting point:260 °C (dec.)(lit.)
  • Boiling point:56.12°C
  • alpha -53.7 º (c=0.7,water)
  • Density 2.47±0.1 g/cm3(Predicted)
  • storage temp. -20°C
  • solubility H2O: 10 mg/mL pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble., clear, colorless
  • form powder
  • pka1.00±0.60(Predicted)
  • color white
  • Water Solubility 50 mg/mL
  • Merck 14,2708
  • BRN 52645
  • NIST Chemistry ReferenceAdenosine 3',5'-cyclic monophosphate(60-92-4)
  • EPA Substance Registry SystemAdenosine, cyclic 3',5'-(hydrogen phosphate) (60-92-4)
Safety Information
MSDS
Cyclic AMP Usage And Synthesis
  • Chemical PropertiesWhite crystalline powder
  • UsescAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3?: 5?-cyclic monophosphate. In the presence of adenosine 3?:5?-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3?:5?-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3?,5?-cyclic monophosphate.
  • DefinitionChEBI: A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase.
  • Biochem/physiol ActionsNaturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
  • Safety ProfileHuman mutation data reported.When heated to decomposition it emits toxic fumes ofPOx and NOx.
Cyclic AMP Preparation Products And Raw materials
Cyclic AMP(60-92-4)Related Product Information
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