3-Aminobenzylamine

Product Name3-Aminobenzylamine
CAS4403-70-7
MFC7H10N2
MW122.17
EINECS412-230-2
MOL File4403-70-7.mol

Chemical Properties

Melting point	41-45 °C
Boiling point	134°C/4mmHg(lit.)
Density	1.093±0.06 g/cm3(Predicted)
Flash point	>110℃
storage temp.	2-8°C, protect from light
solubility	soluble in Methanol
pka	9.22±0.10(Predicted)
form	Low Melting Solid
color	Pale brown
InChI	1S/C7H10N2/c8-5-6-2-1-3-7(9)4-6/h1-4H,5,8-9H2
InChIKey	ZDBWYUOUYNQZBM-UHFFFAOYSA-N
SMILES	NCc1cccc(N)c1
CAS DataBase Reference	4403-70-7(CAS DataBase Reference)

Safety Information

Hazard Codes	N,C
Risk Statements	34-51/53-22
Safety Statements	26-36/37/39-61-45-22
RIDADR	3259
WGK Germany	3
TSCA	TSCA listed
HazardClass	8
PackingGroup	III
HS Code	29215900
Storage Class	8B - Non-combustible corrosive hazardous materials
Hazard Classifications	Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 Eye Dam. 1 Skin Corr. 1B

Usage And Synthesis

Application

m-Aminobenzylamine is an important organic dye and pharmaceutical intermediate. It can also be used as a curing agent for epoxy resins and in the polymerization of olefin compounds to prepare insulated cables. Synthetic methods for benzylamine compounds include the reaction of benzaldehyde with hydroxylamine hydrochloride, direct amination of halobenzyl with aminoamine, amination with hexamethylenetetramine, and amination with phthalimide. Alfred prepared m-aminobenzylamine using m-nitrobenzoic acid as a raw material; other methods involve introducing a CN group onto the benzene ring followed by catalytic hydrogenation.

Chemical Properties

Pale brown low melting solid

Synthesis Reference(s)

Synthetic Communications, 25, p. 863, 1995 DOI: 10.1080/00397919508013422

Synthesis

3717-30-4

4403-70-7

The general procedure for the synthesis of 3-aminobenzylamine from the compound (CAS:3717-30-4) is as follows: Example 18: 16.6 g (0.1 mol) of m-nitrobenzaldehyde oxime made in Example 15, 9.5 g (0.05 mol) of p-toluenesulfonic acid, 0.5 g of 5% Pt-C catalyst and 75 mL of dioxane were added to a sealed glass vessel. Vigorous stirring was carried out under hydrogen-filled conditions. The reaction was continued at 30°C to 40°C for 8 hours. Upon completion of the reaction, the mixture was filtered to remove the catalyst, followed by the addition of 35 g (0.3 mol) of 35% aqueous sodium hydroxide. After stirring, the mixture was allowed to stand until layered. The lower layer was separated and discarded and the upper layer was distilled. Finally 8.9 g of m-aminobenzylamine was obtained in 72.9% yield and 99.3% purity by gas chromatography.

References

[1] Patent: US4751328, 1988, A

Preparation Products And Raw materials

3-Aminobenzylamine Supplier

3-Aminobenzylamine manufacturers

Related Product Information

Send Inquriy