三角叶薯蓣皂苷
三角叶薯蓣皂苷 性质
| 熔点 | 298-300 °C (decomp) |
|---|---|
| 密度 | 1.42±0.1 g/cm3(Predicted) |
| 储存条件 | 4°C, protect from light |
| 形态 | 固体 |
| 酸度系数(pKa) | 12+-.0.70(Predicted) |
| 颜色 | 白色至米白色 |
三角叶薯蓣皂苷 用途与合成方法
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ERK1
|
ERK2
|
Akt
|
Human Endogenous Metabolite
|
Deltonin inhibits ERK1/2 and AKT activation. Deltonin (0.5-8 μM) significantly inhibits the proliferation of several colon cancer cell lines including SW480, SW620, LOVO and C26, with IC 50 s of 1.3, 1.29, 2.11 and 1.22 μM. Deltonin also causes G2-M phase arrest and induces apoptosis in C26 cells. Deltonin (0-5 μM) decreases the phosphorylation of AKT and ERK1/2 levels in MDA‑MB‑231 cells. Deltonin (0.5-8 μM) also dose-dependently inhibits the proliferation, and causes apoptosis with ROS production in MDA‑MB‑231 cells.
Deltonin (20 and 40 mg/kg, p.o.) reduces the tumor growth of 37.7% and 56.7%, and causes a 50-day survival rate of 60% and 50%, respectively, in mice. Deltonin also inhibits tumor angiogenesis in mice.
三角叶薯蓣皂苷 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-N2283 | 三角叶薯蓣皂苷 | 55659-75-1 | 1 mg | 995 |
| 2026-09-15 | HY-N2283 | 三角叶薯蓣皂苷 | 55659-75-1 | 5mg | 3588 |
