Tris(dibenzylideneacetone)dipalladium is used as a source of soluble Pd(0), in particular as a catalyst for various coupling reactions. Examples of reactions using this reagent are the Negishi coupling, Suzuki coupling, Carroll rearrangement, and Trost asymmetric allylic alkylation, as well as Buchwald–Hartwig amination
A process for the preparation of tris(dibenzylideneacetone)dipalladium (chloroform) comprising the steps of:
(a) reacting a Pd(II) complex with an alkali metal halide in at least one alcohol solvent; and
(b) reacting the product of step (a) with a mixture comprising dibenzylideneacetone, chloroform and an inorganic base to form Pd2(dba)3.CHCl3.
