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BECLOMETHASONE

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BECLOMETHASONE Basic information
BECLOMETHASONE Chemical Properties
  • Melting point:217- 222°C (dec.)
  • Boiling point:600.2±55.0 °C(Predicted)
  • Density 1.35±0.1 g/cm3(Predicted)
  • storage temp. 2-8°C
  • pka12.17±0.70(Predicted)
  • Merck 13,1020
  • CAS DataBase Reference4419-39-0(CAS DataBase Reference)
Safety Information
  • Safety Statements 24/25
  • WGK Germany 3
  • HS Code 29372900
MSDS
BECLOMETHASONE Usage And Synthesis
  • Chemical PropertiesWhite to Off-White Solid
  • UsesGlucocorticoid. Beclomethasone is used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).
  • DefinitionChEBI: A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively.
  • brand nameBeclovent (GlaxoSmithKline); Beconase (GlaxoSmithKline); Qvar (3M Pharmaceuticals); Vanceril (Schering).
  • Biological FunctionsThe topical anti-inflammatory potency for beclomethasone dipropionate (BDP) is approximately 5,000 times greater than hydrocortisone, 500 times greater than betamethasone or dexamethasone, and approximately five times greater than fluocinolone acetonide or triamcinolone acetonide, as measured by vasoconstrictor assay.
  • Clinical UseBeclomethasone, a 9α-chloro analogue of betamethasone, is a potent glucocorticoid with approximately half the potency of its fluoro analogue. It is used topically as its dipropionate derivative in inhalation aerosol therapy for asthma and rhinitis but not for treatment of steroid-responsive dermatoses.
BECLOMETHASONE Preparation Products And Raw materials
BECLOMETHASONE(4419-39-0)Related Product Information
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