In the hydrothermal reactor, terminal chlorinated dodecanoic acid and NaOH solution were added, and the reaction was stopped after hydrothermal alkaline hydrolysis at the specified temperature for a specified time, and the crude product of terminal hydroxydodecanoic acid was obtained by filtration. The pure product of terminal hydroxydodecanoic acid used for structure and purity identification was obtained by acidifying the crude product of terminal chlorinated 12-acid, and then purified by recrystallization with petroleum ether (60-90 ), and the pure product of terminal hydroxydodecanoic acid used for application performance testing was obtained by neutralization of the above. The crude product was derivatized by methyl esterification with boron trifluoride - ether/methanol solution, extracted with anhydrous ether, and the upper ether layer was analyzed by GC for the content of each component (area normalization method), and the yield (Y) of terminal hydroxy12 acid was calculated.
