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Hyodeoxycholic acid

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Hyodeoxycholic acid Basic information
Hyodeoxycholic acid Chemical Properties
  • Melting point:200-201 °C (lit.)
  • alpha D20 +8° (alc)
  • Boiling point:437.26°C (rough estimate)
  • Density 0.9985 (rough estimate)
  • refractive index 1.4460 (estimate)
  • storage temp. Refrigerator
  • solubility Solubility in methanol, very faint turbidity. Slightly soluble in alcohol, acetone, ether and very slightly soluble in chloroform.
  • pka4.76±0.10(Predicted)
  • Water Solubility 5.889mg/L(25 ºC)
  • Merck 14,4857
  • InChIKeyDGABKXLVXPYZII-SIBKNCMHSA-N
  • CAS DataBase Reference83-49-8(CAS DataBase Reference)
Safety Information
MSDS
Hyodeoxycholic acid Usage And Synthesis
  • Chemical PropertiesWhite Solid
  • UsesProtected β-Hyodeoxycholic Acid (H998105), a potential bile acid metabolite.
  • UsesLabelled Hyodeoxycholic Acid. Unlabelled version is isolated from pig bile. Antitumor agent
  • UsesIt is isolated from pig bile. Antitumor agent
  • UsesLabelled β-Hyodeoxycholic Acid
  • DefinitionChEBI: A member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6.
  • Purification MethodsCrystallise -hyodeoxycholic acid from EtOAc or Me2CO. The K salt separates in needles from an alcoholic solution of the acid when an equivalent of KOMe is added (see lithocholic acid). [Weiland & Gumlish Hoppe Seyler's Z Physiol Chem 215 18 1933, Windaus & Bohne Justus Liebigs Ann Chem 433 278 1923, Beilstein 10 III 1631.]
Hyodeoxycholic acid Preparation Products And Raw materials
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