磺草酮
磺草酮 性质
| 熔点 | 139° |
|---|---|
| 沸点 | 574.5±50.0 °C(Predicted) |
| 密度 | 1.428±0.06 g/cm3(Predicted) |
| 储存条件 | Inert atmosphere,Room Temperature |
| 溶解度 | 可溶于氯仿（少许）、甲醇（少许） |
| 形态 | 固体 |
| 酸度系数(pKa) | 3.22±0.50(Predicted) |
| 颜色 | 白色至米白色 |
| Merck | 13,8979 |
| BRN | 8155739 |
| Henry's Law Constant | 1.7×106 mol/(m3Pa) at 25℃, Maniere et al. (2011) |
| 主要应用 | 农业领域 环境香氛 |
| InChI | 1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3 |
| InChIKey | PQTBTIFWAXVEPB-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)c1ccc(c(Cl)c1)C(=O)C2C(=O)CCCC2=O |
| EPA化学物质信息 | 1,3-Cyclohexanedione, 2-[2-chloro-4-(methylsulfonyl)benzoyl]- (99105-77-8) |
磺草酮 用途与合成方法
HPPD
The results show that sulcotrione behaves as time-independent reversible inhibitor. Similar results are previously described for natural β-triketones, and for the synthetic β-triketone NTBC. However it is the first time that such behavior is observed using a purified hydroxyphenylpyruvate dioxygenase (HPPD) and a synthetic β-triketone, namely sulcotrione. Inhibition kinetic analysis, performing with 3 hydroxyphenylpyruvate (HPP) and sulcotrione concentrations, show that the apparent K M increasing with sulcotrione concentration. This behavior is consistent with the data present in the literature, describing sulcotrione as a competitive inhibitor of HPPD.
大鼠急性经口LD50>5000mg/kg。兔急性经皮LD50>4000mg/kg。兔皮肤对其吸收率不高，对皮肤无刺激性，对兔眼中度刺激;对豚鼠皮肤强致敏性。大鼠急性吸入LC50 (4h)1.6mg/L。大鼠 NOEL 数据(2y)100mg/L[0.5mg/(kg ·d)]。ADI(EC)0.0004mg/kg[2008];(BfR)0.007mg/kg[2006]。对大鼠和兔无致畸作用，且无基因毒性。
安全信息
| 危险品标志 | Xi,N,Xn |
|---|---|
| 危险类别码 | 43-50/53-48/22-63 |
| 安全说明 | 36/37-61-60-22 |
| 危险品运输编号 | UN 3077 9 / PGIII |
| WGK Germany | 2 |
| 海关编码 | 29309090 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 危害水生环境-急性危害 类别1 危害水生环境-长期危害 类别1 生殖毒性 类别2 皮肤致敏物 类别1A 特异性靶器官毒性-反复接触类别2 |
磺草酮 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-107368R | 磺草酮 | 99105-77-8 | 5 mg | 580 |
| 2026-09-15 | HY-107368R | 磺草酮 | 99105-77-8 | 10 mg | 875 |
