Dabcyl-GABA-RPKPVE-Nva-WR-Glu(EDANS)-AK-NH2 is a fluorogenic substrate for matrix metalloproteinase-3 (MMP-3).1 Upon enzymatic cleavage by MMP-3 at Glu-Nva, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify MMP-3 activity. EDANS displays excitation/emission maxima of 340/485 nm, respectively.WARNING This product is not for human or veterinary use.
References
[1] BOB BEEKMAN . Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media[J]. FEBS Letters, 1996, 390 2: Pages 221-225. DOI: 10.1016/0014-5793(96)00665-5
