Pyrazosulfuron-ethyl is a new highly active sulfonylurea herbicide that has been widely used for weed control in a variety of vegetables and other crops.It prevents the synthesis of essential amino acids by blocking cell division and weed growth.
ChEBI: Pyrazosulfuron-ethyl is a member of pyrazoles.
Pyrazosulfuron-ethyl is commercially produced via a sulfonylurea synthesis starting from ethyl 5-amino-1-methylpyrazole-4-carboxylate, which is sulfonylated with 2-(chlorosulfonyl)benzoic acid ethyl ester under basic conditions to form the sulfonamide. This intermediate is activated with phosgene or triphosgene to generate the sulfonyl isocyanate, which undergoes condensation with 2-amino-4,6-dimethoxypyrimidine to construct the urea bridge. Final cyclisation, hydrolysis, and recrystallisation yield pyrazosulfuron-ethyl.
Broad-spectrum activity, absorbed by roots and translocated through out plant by controlling the synthesis of amino acids. Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS
