Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Amide >  Maleimide


Basic information Safety Related Supplier
Maleimide Basic information
Maleimide Chemical Properties
  • Melting point:91-93 °C (lit.)
  • Boiling point:97-103°C 5mm
  • Density 1,2493 g/cm3
  • refractive index 1.4543 (estimate)
  • Flash point:97-103°C/5mm
  • storage temp. Inert atmosphere,Room Temperature
  • pka8.52±0.20(Predicted)
  • form Fine Crystalline Powder
  • color White to slightly yellow
  • Water Solubility SOLUBLE
  • λmax280nm(EtOH)(lit.)
  • BRN 106910
  • CAS DataBase Reference541-59-3(CAS DataBase Reference)
  • NIST Chemistry Reference1H-pyrrole-2,5-dione(541-59-3)
  • EPA Substance Registry System1H-Pyrrole-2,5-dione (541-59-3)
Safety Information
Maleimide Usage And Synthesis
  • Chemical Propertiesslight yellow crystalline powder
  • UsesRhodium-catalyzed conjugate arylation with arylboronic acids.1
  • UsesReacts quantitatively with sulfhydryl groups.Maleimide is used to immobilize the bovine serum albumin-boronic acid conjugates in association with silica beads. Its nanoparticle surface favors the conjugation with cell penetration peptides. It is involved in Rhodium-catalyzed conjugate arylation with arylboronic acids. It is actively involved in Michael additions and Diels-Alder reactions by the addition across the double bond. It acts as crosslinking reagents in polymer chemistry.
  • DefinitionChEBI: A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure.
  • General Description
    Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.
  • HazardA poison.
  • Safety ProfilePoison by intraperitoneal and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Purification MethodsPurify it by sublimation in a vacuum. The UV has max at 216 and 280nm in EtOH. [de Wolf & van de Straete Bull Soc Chim Belg 44 288 1935, UV: Rondestvedt et al. J Am Chem Soc 78 6115 1956, IR: Chiorboli & Mirone Ann Chim (Rome) 42 681 1952, Beilstein 21/10 V 3.]
Maleimide Preparation Products And Raw materials
Maleimide(541-59-3)Related Product Information
  • Company Name:career henan chemical co Gold
  • Tel:+86-0371-55982848
  • Company Name:Shanghai RC Chemicals Co., Ltd. Gold
  • Tel:18217085189
  • Company Name:Jinan Aery Pharmaceutical Co,.Ltd Gold
  • Tel:0531-81263406
  • Company Name:Zheda Panaco Chemical Engineering Co., Ltd Gold
  • Tel: 0571-86770761-
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-