盐酸苯氟雷司
![盐酸苯氟雷司 结构式](https://img.chemicalbook.com/CAS/GIF/23642-66-2.gif)
盐酸苯氟雷司 用途与合成方法
HNF4α
Benfluorex hydrochloride consistently activates insulin promoter activity as measured by an increased number of GFP-positive cells. Benfluorex hydrochloride increases the number of GFP-positive cells in a dose-responsive manner and increases the level of endogenous insulin mRNA. Consistent with being HNF4α activator, Benfluorex hydrochloride stimulates HNF4α expression. Benfluorex hydrochloride alters HNF4α protease sensitivity, while the inactive control compound does not. Benfluorex hydrochloride decreases, in a concentration-dependent manner, the synthesis of acid-soluble products and ketone bodies from oleate, whereas the production of 14 CO 2 into citric acid cycle is markedly increased by Benfluorex hydrochloride. Benfluorex hydrochloride inhibits in a dose-dependent manner the rates of gluconeogenesis from lactate/pyruvate (10/1 nM).
安全信息
危险品标志 | Xi |
---|---|
WGK Germany | 2 |
RTECS号 | KL8275000 |
Hazard Note | Irritant |
海关编码 | 2916399090 |
毒性 | LD50 intraperitoneal in mouse: 108mg/kg |
盐酸苯氟雷司 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2025-02-08 | HY-B1058 | 盐酸苯氟雷司 | 23642-66-2 | 500 mg | 350 |
2025-02-08 | HY-B1058 | 盐酸苯氟雷司 | 23642-66-2 | 10mM * 1mLin DMSO | 550 |