Acid Violet 43

Acid Violet 43 is an anthraquinone color that functions as a colorant in cosmetic formulations (Wenninger, Canterbery, and McEwen 2000). Batches of Acid Violet 43 that are certified by the Food and Drug Administration (FDA) as meeting the standards and specifications described in the Code of Federal Regulations (21 CFR 73 & 74) are named Ext. D & C Violet No. 2 (FDA 1976). Most of the available safety test data are from studies of Ext. D & C Violet No. 2 conducted to support FDA listing this color for drug and cosmetic use.

Acid Violet 43 has a bluish violet hue in daylight and is slightly redder in artificial light (tungsten) (Society of Dyers and Colourists 1971a). It is soluble in alcohol (Society of Dyers and Colourists 1971b) and water (Hazleton Laboratories, Inc. 1968). It is blue in concentrated sulfuric acid, olive-brown after dilution, accompanied by a purple precipitate.

Acid Violet 43 is an anthraquinone colour used in semi-permanent hair dye formulations at a maximum concentration of 0.5% active dye. According to the EU Cosmetics Directive 76/768/EEC, Annex IV Part I List of Colouring Agents, Acid Violet 43 is allowed as CI 60730 in cosmetic products except those intended to come into contact with mucous membranes.

Acid Violet 43 can be prepared by sulfonating the anthraquinone color, C.I. 60725 and converting it to the sodium salt (Society of Dyers and Colourists 1971b).
Will be 1,4-Dihydroxyanthracene-9,10-dione or anthracene-1,4,9,10-tetraol or 1-Bromo-4-hydroxyanthraquinone (or 1-Chloro-4-hydroxyanthracene-9,10-dione) and reaction p-Methylaniline, then stlfonation, and translated into sodium salt.

Non flammable

Acid violet 43 is used for the dyeing of wool and its products. It can be used for dyeing and printing of wool, silk, nylon and its fabrics, as well as for leather dyeing.

In 2001, the Cosmetic Ingredient Review (CIR) Expert Panel (Panel) published a safety assessment with the conclusion that Acid Violet 43 is safe for use in hair dye formulations when free of impurities except for the following: ≤18% volatile matter (at 135°C) and chlorides and sulfates (calculated as sodium salts); ≤0.4% water-insoluble matter; ≤0.2% 1-hydroxy-9,10-anthracenedione; ≤0.2% 1,4-dihydroxy-9,10-anthracenedione; ≤0.1% p-toluidine; ≤0.2% p-toluidine sulfonic acids, sodium salts; ≤1% subsidiary colors; ≤20 ppm lead (as Pb); ≤3 ppm arsenic (as As); ≤1 ppm mercury as (Hg); and ≥80% total color.
Amended Safety Assessment of Acid Violet 43 as Used in Cosmetics

blue purple. Soluble in alcohol. The strong sulfuric acid in blue, diluted for olive brown, then a purple precipitation.

Standard	Light Fastness	Soaping		Persperation Fastness	Oxygen bleaching		Fastness to seawater
		Fading	Stain		Fading	Stain	Fading	Stain
ISO	5	1-2	1-2	3-4	1	5	2	1
AATCC	3	1	1	2	1	1	2	2