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Alizarin Red S

Product NameAlizarin Red S
CAS130-22-3
MFC14H7NaO7S
MW343.27
EINECS204-981-8
MOL File130-22-3.mol

Chemical Properties

Melting point	>250°C
Boiling point	287-289°C
storage temp.	room temp
solubility	H2O: soluble1mg/mL
form	Powder
Colour Index	58005
pka	4.5, 11(at 25℃)
color	Various
PH Range	4.3(yellow)-6.3(violet)
Water Solubility	Soluble in water and alcohol.
λmax	556nm, 596nm, 423nm, 546nm
Merck	14,8573
BRN	4117090
Stability	Stable. Incompatible with strong oxidizing agents.
Biological Applications	Detecting Candida,lactic acid bacteria,microorganisms; treating gastropathy,viral diseases
Major Application	Nanocomposite material, chemical mechanical polishing, optical fibers, display device, carbon nanotubes, textiles, determination of aluminum,iron,copper,manganese,zinc,calcium,magnesium,zirconium,hafnium,molybdenum,uranium,vanadium, detergents, hair dyes, determination of proteins,clotrimazole,ketoconazole,piroxicam,and tenoxicam
InChI	1S/C14H8O7S.Na/c15-11-6-3-1-2-4-7(6)12(16)10-8(11)5-9(22(19,20)21)13(17)14(10)18;/h1-5,17-18H,(H,19,20,21);/q;+1/p-1
InChIKey	HFVAFDPGUJEFBQ-UHFFFAOYSA-M
SMILES	[Na+].Oc1c(O)c(cc2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O
CAS DataBase Reference	130-22-3(CAS DataBase Reference)
EPA Substance Registry System	Sodium alizarinesulfonate (130-22-3)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	CB1095300
TSCA	TSCA listed
HS Code	32049090
Storage Class	11 - Combustible Solids

MSDS

Provider	Language
9,10-Dihydro-3,4-dihydroxy-9,10-dioxo-2-anthracenesulfonic acid sodium salt	English
SigmaAldrich	English
ACROS	English
ALFA	English

Usage And Synthesis

Chemical Properties

yellow-orange powder

Uses

Alizarin Red S sodium salt is used as a chromogenic agent for the colorimetric determination of dothiepin hydrochloride in pharmaceutical formulations. It is also used as an ion-pair reagent for the spectrophotometric assay of fexofenadine in pharmaceuticals. It acts as a colorometric pH indicator in the range of 3.8-5.4. Further, it is used in a biochemical assay to determine the presence of calcific deposition by cells of an osteogenic lineage.

Uses

Alizarin Red S is used in the biochemical assay to determine the presence of calcium.

Preparation

Alizarin Red S was prepared by reacting 1,2-Dihydroxyanthracene-9,10-dione with fuming sulfuric acid sulphonate, and translated into Sodium salt.

Definition

ChEBI: An organic sodium salt having 3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate as the counterion. It is commonly used to stain embryo skeletons in cleared whole mounts, usually of small mammals.

Biochem/physiol Actions

Alizarin Red S is used for the staining of cartilage and bone. It reacts with calcium, thereby helping in the diagnosis of calcium deposits. It is also used to study carbohydrate–boronic acid interactions.

Properties and Applications

dark blue light red (chromium), brilliant yellow red (aluminum). Claybank powder. Soluble in Cellosolve, slightly soluble in ethanol and Acetone. In concentrated sulfuric acid to orange, dilution to pale yellow.

Standard	Ironing Fastness	Light Fastness	Fulling		Persperation Fastness	Soaping	Water
Standard	Ironing Fastness	Light Fastness	Alkali	Acid	Persperation Fastness	Soaping	Water
ISO	3	6	4-5	1	4-5	5	5
AATCC	3-4	6-7	3		5	4	4

Alizarin Red S

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