叫棒曲霉素
叫棒曲霉素 性质
| 熔点 | 108-111 °C |
|---|---|
| 比旋光度 | D21 -6.2° (chloroform) |
| 沸点 | 197.46°C (rough estimate) |
| 密度 | 1.1993 (rough estimate) |
| 折射率 | 1.4300 (estimate) |
| 闪点 | 2℃ |
| 储存条件 | −20°C |
| 溶解度 | 可溶于乙酸乙酯50mg/mL |
| 酸度系数(pKa) | 11.69±0.20(Predicted) |
| 形态 | 晶体或结晶粉末 |
| 颜色 | 白色 |
| Merck | 13,7125 |
| BRN | 149675 |
| Henry's Law Constant | 9.0×104 mol/(m3Pa) at 25℃, HSDB (2015) |
| 稳定性 | 自购买之日起 1 年内保持稳定。 DMSO 或乙醇溶液可在 -20°C 下保存长达 1 个月。 |
| 主要应用 | 清洁产品 化妆品 食品和饮料 个人护理 |
| InChI | 1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2 |
| InChIKey | ZRWPUFFVAOMMNM-UHFFFAOYSA-N |
| SMILES | OC1OCC=C2OC(=O)C=C12 |
| CAS 数据库 | 149-29-1(CAS DataBase Reference) |
| (IARC)致癌物分类 | 3 (Vol. 40, Sup 7) 1987 |
| EPA化学物质信息 | Patulin (149-29-1) |
叫棒曲霉素 用途与合成方法
Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. glutathione in Hep G2 cells. Patulin is an antibiotic. Patulin-induced nephropathy and gastrointestinal tract malfunction have been demonstrated in several animal models. The oral LD50 value of patul in ranges between 29 and 55 mg/kg body weight in rodents and 170 mg/kg body weight in poultry. The World Health Organization considers patulin cytotoxic and established a safety level of patulin in ap ple juice at 50 μM. At 100-200 μM, patulin can directly increase intracellular oxidative stress in HEK293 and HL-60 cells. In 1944, this compound was tested in a clinical trial for potential antibiot ic properties to treat the common cold.
安全信息
| 危险品标志 | T,Xn,C,F |
|---|---|
| 危险类别码 | 25-38-48/20/22-40-22-34-11-36-20/21/22-67-36/38-20-63 |
| 安全说明 | 45-36/37-36/37/39-26-16 |
| 危险品运输编号 | UN 3462 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS号 | LV2625000 |
| 危险等级 | 6.1(a) |
| 包装类别 | I |
| 海关编码 | 29419090 |
| 存储类别 | 3- 易燃液体 |
| 危险性类别 | 急性毒性 类别4 经皮 急性毒性 类别4 吸入 急性毒性 类别4 经口 眼部刺激 类别2 易燃液体 类别2 |
| 毒害物质数据 | 149-29-1(Hazardous Substances Data) |
| 毒性 | LD50 s.c. in mice: 10-15 mg/kg (Kinosita, Shikata) |
叫棒曲霉素 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-06-05 | HY-N6779R | 叫棒曲霉素 | 149-29-1 | 1 mg | 2000 |
| 2026-06-05 | HY-N6779R | 叫棒曲霉素 | 149-29-1 | 5 mg | 6000 |
