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Imperatorin

Basic information Description References Safety Related Supplier
Imperatorin Basic information
Imperatorin Chemical Properties
Safety Information
MSDS
Imperatorin Usage And Synthesis
  • DescriptionImperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.
  • Referenceshttps://www.scbt.com/scbt/product/imperatorin-482-44-0
    https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
    https://en.wikipedia.org/wiki/Imperatorin
  • Chemical PropertiesWhite Solid
  • UsesImperatorin (cas# 482-44-0) is a compound useful in organic synthesis.
  • DefinitionChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.
  • General Description
    This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
  • Biochem/physiol ActionsImperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Imperatorin(482-44-0)Related Product Information
ImperatorinSupplierMore
  • Company Name:ShangHai YuanYe Biotechnology Co., Ltd. Gold
  • Tel:15800763013 021-61312847-
  • Email:3008007399@qq.com
  • Products Intro:Product Name:Imperatorin
    CAS:482-44-0
    Purity:HPLC≥98% Package:20mg
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  • Company Name:Chengdu Chuanyan Medical Technology co. ,Ltd Gold
  • Tel:18280298385
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  • Products Intro:Product Name:Imperatorin
    CAS:482-44-0
    Purity:HPLC≥98% Package:20MG;50MG;100MG;200MG;1G;10G;多规格定制
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  • Company Name:J & K SCIENTIFIC LTD.
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  • Products Intro:Product Name:Imperatorin, 98%
    CAS:482-44-0
    Purity:98% Package:10MG;50MG
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456-
  • Email:sales@BioChemBest.com
  • Products Intro:Product Name:MARMELOSIN (IMPERATORIN)
    CAS:482-44-0
    Remarks:C11428
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  • Company Name:Chemsky(shanghai)International Co.,Ltd.
  • Tel:021-50135380
  • Email:shchemsky@sina.com
  • Products Intro:Product Name:IMperatorin
    CAS:482-44-0
    Purity:98%
  •