Perfluorodecalin (PFD) is a chemically and biologicallyinert biomaterial and, as many perfluorocarbons, is alsohydrophobic, radiopaque and has a high solute capacity forgases such as oxygen.
Perfluorodecalin is a fluorocarbon and derivative of decalin, and used in cosmetics and beauty products as to dissolve and deliver oxygen to the skin in formulas (Wikipedia). It is also used as a skin conditioning agent, detangler, and solvent in some formulas. Perfluorodecalin's ability to dissolve oxygen is thought to revitalize skin and reduce wrinkles, increasing the partial pressure of oxygen (pO2), according to research.
Some studies have shown that formulas that include Perflurodecalin improve the skin's barrier function resulting in increased moisturizing efficacy. However, there are no studies to prove that added oxygen can actually repair wrinkled skin or prevent lines from forming. Conversely, too much oxygen can enhance the number of unstable oxygen molecules which cause free radical damage.
Perfluorodecalin is used as a building block reagent as well maintains ability to dissolve gases such as oxygen and increase oxygen to a location allowing for medicinal uses such as preserving tissue after pancreas transplants.
Perfluorodecalin is a fluorous solvent generally used as a primary component of the fluorous biphasic system (FBS) or the fluorous multiphasic system (FMS) in synthetic chemistry. It is also used as an additive to increase oxygen solubility in fermentation media.
ChEBI: A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.
Poison by intravenous route. When heated to decomposition it emits toxic vapors of Fí.
