ChemicalBook Product Catalog Catalyst and Auxiliary UV absorbers 2,2'-Dihydroxy-4-methoxybenzophenone

2,2'-Dihydroxy-4-methoxybenzophenone

Product Name2,2'-Dihydroxy-4-methoxybenzophenone
CAS131-53-3
MFC14H12O4
MW244.24
EINECS205-026-8
MOL File131-53-3.mol

Chemical Properties

Melting point	73-75 °C(lit.)
Boiling point	170-175 °C1 mm Hg(lit.)
Density	1.2379 (rough estimate)
vapor pressure	0-0Pa at 20-25℃
refractive index	1.5389 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	7.11±0.35(Predicted)
color	Off-White to Yellow
Merck	14,3303
Stability	Stable. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions	UV ABSORBER
Cosmetic Ingredient Review (CIR)	2,2'-Dihydroxy-4-methoxybenzophenone (131-53-3)
InChI	1S/C14H12O4/c1-18-9-6-7-11(13(16)8-9)14(17)10-4-2-3-5-12(10)15/h2-8,15-16H,1H3
InChIKey	MEZZCSHVIGVWFI-UHFFFAOYSA-N
SMILES	COc1ccc(c(O)c1)C(=O)c2ccccc2O
LogP	2.33 at 23.5℃
CAS DataBase Reference	131-53-3(CAS DataBase Reference)
NIST Chemistry Reference	Dioxybenzone(131-53-3)
EPA Substance Registry System	Dioxybenzone (131-53-3)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	DJ1049500
TSCA	TSCA listed
HS Code	29145090
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
Hazardous Substances Data	131-53-3(Hazardous Substances Data)

MSDS

Provider	Language
2,2'-Dihydroxy-4-methoxybenzophenone	English
SigmaAldrich	English

Usage And Synthesis

Chemical Properties

Light yellow powder. Freezing point 68℃, boiling point 170-175℃(0.133kPa), relative density 1.382(25℃).Solubility at 25℃(g/100g solvent): benzene 46.6, n-hexane 2.3, 95% ethanol 21.4, carbon tetrachloride 22.2, methylethyl ketone 55.3, plasticiser DOP 31.1, insoluble in water.

Application

Dioxybenzone is a compound used in sunscreen formulations to block out UVB and UVA harmful rays. Broad-spectrum sunscreens often contain a number of chemical ingredients that absorb UVA and UVB radiation. Many sunscreens contain UVA-absorbing avobenzone or a benzophenone (such as dioxybenzone, oxybenzone, or sulisobenzone), in addition to UVB-absorbing chemical ingredients (some of which also contribute to UVA protection).

Uses

benzophenone-8 (dioxybenzone) is an FDA-approved sunscreen chemical with uVA-absorption capabilities. It also can protect product degradation arising from uV-light exposure. It has an approved usage level of 3 percent in the united States.

Preparation

preparation by condensation of salicylic acid and m-methoxyphenol.

Definition

ChEBI: 2,2'-Dihydroxy-4-methoxybenzophenone is a member of benzophenones.

General Description

Dioxybenzone, also known as benzophenone-8, is an organic compound and a derivative of benzophenone used commercially in sunscreens. It absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3%.

Reactivity Profile

An alcohol and a ketone. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.

Fire Hazard

Flash point data for 2,2'-Dihydroxy-4-methoxybenzophenone are not available. 2,2'-Dihydroxy-4-methoxybenzophenone is probably combustible.

2,2'-Dihydroxy-4-methoxybenzophenone

Chemical Properties

Safety Information

MSDS

Usage And Synthesis

Preparation Products And Raw materials

2,2'-Dihydroxy-4-methoxybenzophenone Supplier

2,2'-Dihydroxy-4-methoxybenzophenone manufacturers

Related Product Information