Isopropenylmagnesium bromide (iPrMgBr) solution (0.5 M in THF) has been used in the Grignard reaction, a key step the in preparation of zofenoprilat and (S)-(?)-phosphonotrixin. It can also be used for the regioselective ring opening of an optically active epoxy alcohol in the total synthesis of (+)-desepoxyasperdiol.
This product, 1.0 M in 2-methyltetrahydrofuran aligns with Safer Solvents and Auxiliaries, Use of Renewable Feedstocks and Inherently Safer Chemistry for Accident Prevention.
reaction type: Grignard Reaction
The Preparative Method of 2-Propenylmagnesium Bromide-Copper(I) Iodide: prepared in situ under anhydrous conditions by reacting 2-propenylmagnesium bromide (1) with Copper(I) Iodide (2) in varying molar ratios.
