clear yellow to red-brown solution
4-Fluorophenylmagnesium bromide solution (Grignard reagent) can be used as a reagent in the synthesis of:
- Useful key intermediate in the synthesis of paroxetine.
- Arylsulfides via cross-coupling reaction with thiols.
- 4-Arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as androgen receptor antagonists.
- Grignard intermediate for preparing aprepitant.
4-Fluorophenylmagnesium bromide is used as a reagent for the introduction of the 4-Fluorophenyl group.
reaction type: Grignard Reaction