Bis(2,4-pentanedionato-O,O')palladium(II)

yellow orange needles

Palladium(II) Acetylacetonate is an active anticancer agent. Exhibits growth inhibitory effect more than cisplatin in several cancer cells and treatment with Palladium(II) Acetylacetonate inhibits H460 cells. Palladium(II) Acetylacetonate is a catalyst for various organic transformations.

Palladium(II) acetylacetonate (Pd(acac)₂) was used in the following studies:

• Typical high-temperature organic solution phase protocol for the preparation of monodisperse CuPd alloy nanoparticles (NPs).
• Preparation of [(NHC)Pd(acac)L] (where L=Me, NHC = N-heterocyclic carbene) complexes. These complexes efficiently catalyze the Heck reaction of activated aryl bromides.
• As catalyst in the decarboxylative cross-coupling of arylcarboxylic acids with aryl halides.

Palladium(II) acetylacetonate (Pd(acac)₂) is a metal-organic complex. Sublimation of Pd(acac)₂ has been investigated by thermogravimetry and XRD. The temperature range for the sublimation of Pd(acac)₂, without undergoing thermal decomposition, was determined to be 100-160°C in the presence of inert gas helium.

Highly flammable

It can be recrystallised from *C6H6/pet ether and sublimes in vacuo. It is soluble in heptane, *C6H6 (1.2% at 20o, 2.2 at 40o), toluene (0.56% at 20o, 1.4% at 40o) and acetylacetone (1.2% at 20o, 0.05% at 40o). [West & Riley J Inorg Nucl Chem 5 295 1957/8, Fernelius & Bryant Inorg Synth V 105 1957, Beilstein 1 IV 3676.]