Grain protectant, insecticide, acaricide.
trans-Methacrifos is used as a pesticide used to protect crops and vegetation.
ChEBI: Methacrifos is an organic thiophosphate.
Methacrifos administered in animals is
rapidly metabolized and excreted. The carboxy methyl
ester bond is cleaved as well as the phosphoryl methyl and
vinyl ester bonds. Oxidative desulfuration also occurs.
The acute oral LD50 for rats is
678 mg/kg. Inhalation LC50 (4 h) for rats is 2.2 mg/L
air. NOEL (2 yr) for rats is 0.6 mg/kg b.w. daily. ADI
is 6 μg/kg b.w.
