7-Hydroxycoumarin glucoside

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Tripterygium wilfordii, Artemisia capillaris, and Glechoma longituba.

Skimmin is a useful research chemical with neuroprotective effects.

ChEBI: Skimmin is a member of coumarins and a glycoside.

Renal protecting, anti-inflammation.

A method for the preparation of 7-hydroxycoumarin glucoside, characterized in that said method consists of the following steps: (1) take the whole herb of horseshoe gold, at room temperature with acetone solution tissue crushing extraction 3 times, each time for 10-30 minutes, the combined extract, concentrated under reduced pressure to the extract; (2) extract the extract with the proportion of 10:1 ethyl acetate - methanol mixed solution for 15-18 countercurrent extraction, the combined extract, decompression Recovery of solvent, the extract; (3) the extract will be dispersed with water, through the polyamide resin column, 30-60% ethanol elution, eluent concentration of the crude product; (4) the crude product will be dissolved in methanol, sampling to the silica gel mesh number of 200-300 of the medium-pressure chromatography column, eluted with a mixture of methanol - dichloromethane, the collection of the target components of the section of the eluent, filtration, concentration and low-temperature drying that is to obtain 7-hydroxycoumarin glucoside.